Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin01:26

Directly Acting Muscle Relaxants: Dantrolene and Botulinum Toxin

875
Directly acting muscle relaxants like dantrolene and botulinum toxin (BoNT) have distinct mechanisms and applications. Dantrolene, a hydantoin derivative, acts on the ryanodine receptor (RYR1) in skeletal muscle cells. RYR1 are calcium channels present at the sarcoplasmic reticulum membrane. In response to excitation, they release calcium ions from the sarcoplasmic reticulum to the cytosol. Calcium promotes actin-myosin-mediated contraction of muscles.
The binding of dantrolene to the RYR1...
875
Skeletal Muscle Relaxants: Therapeutic Uses01:31

Skeletal Muscle Relaxants: Therapeutic Uses

711
Skeletal muscle relaxants are used to relax muscle tone and alleviate painful muscle contractions. However, the choice of skeletal muscle relaxants depends on the duration of the surgical procedure in order to minimize potential side effects. Skeletal muscle relaxants like neuromuscular blocking agents [NMBAs] are commonly employed as adjuvants alongside general anesthetics in clinical settings. NMBAs are also used to maintain controlled ventilation during surgery of the larynx or pharynx...
711
Skeletal Muscle Relaxants: Adverse Effects01:21

Skeletal Muscle Relaxants: Adverse Effects

566
Skeletal muscle relaxants are widely used for muscle paralysis and relieving pain following any muscle injury or stiffness. However, depending on the drug type, they can have adverse effects that range from mild to severe. Usually, nondepolarizing neuromuscular blockers have minimal side effects. For example, drugs like d-tubocurarine, cisatracurium, and rocuronium cause hypotension, whereas drugs like baclofen, when stopped abruptly, can lead to the recurrence of spastic conditions.
Unlike...
566

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recruitment, Retention Approaches and Community Engagement in the THRIVE pilot Trial: Lessons Learned from a Food is Medicine Trial.

medRxiv : the preprint server for health sciences·2026
Same author

Ethical Implications of the Slow Code: A Systematic Review of Ethics of Slow Codes in U.S. Hospitals.

Critical care medicine·2026
Same author

Participants' and physiotherapists' views on the delivery of a randomised controlled feasibility trial investigating a bespoke dynamic elastomeric fabric orthosis for women with chronic pelvic girdle pain: a qualitative exploration.

Pilot and feasibility studies·2026
Same author

Infection following foot and ankle surgery : a subanalysis of data captured from the UK Foot and Ankle Thromboembolism (FATE) audit.

The bone & joint journal·2026
Same author

Increased functional network connectivity following cognitive rehabilitation in progressive multiple sclerosis with moderate to severe disabilty: findings from the CogEx study.

Journal of neurology·2026
Same author

Enhancing Therapist Training in the Delivery of Exposure Therapy for Individuals with Anxiety Disorders Using Virtual Reality Simulation: Randomized Feasibility Trial.

JMIR medical education·2026
Same journal

Cross-cultural Adaptation and Psychometric Validation of the Spanish Version of the Thumb Disability Examination (TDX).

Journal of hand therapy : official journal of the American Society of Hand Therapists·2026
Same journal

The contraction test to detect and predict recurrence of stiffness in the proximal interphalangeal joint.

Journal of hand therapy : official journal of the American Society of Hand Therapists·2026
Same journal

Measuring the clavicular kinematics: A systematic review and an exploratory study.

Journal of hand therapy : official journal of the American Society of Hand Therapists·2026
Same journal

Beyond sensory deficits: Cognitive and biomechanical alterations in female patients with carpal tunnel syndrome.

Journal of hand therapy : official journal of the American Society of Hand Therapists·2026
Same journal

Comparative evaluation of user satisfaction in stroke rehabilitation: Wearable vs traditional electromyography biofeedback for wrist and hand dysfunction.

Journal of hand therapy : official journal of the American Society of Hand Therapists·2026
Same journal

The Children's Hand Skills Ability Questionnaire was successfully translated to Malay.

Journal of hand therapy : official journal of the American Society of Hand Therapists·2026
See all related articles

Related Experiment Video

Updated: Nov 5, 2025

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia
10:41

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia

Published on: September 12, 2020

7.6K

Task specific dystonia - a patients' perspective.

Katherine Butler1, Karin Rosenkranz2, Jennifer Freeman3

  • 1University of Plymouth, Faculty of Health, School of Health Professions, Peninsula Allied Health Centre, Derriford Road, Plymouth, United Kingdom, PL6 8BH; University College London, Division of Surgery and Interventional Science, Gower Street, London, UK, WC1E 6BT; London Hand Therapy, King Edwards VII's Hospital, London, W1G 6AA, United Kingdom.

Journal of Hand Therapy : Official Journal of the American Society of Hand Therapists
|May 21, 2021
PubMed
Summary
This summary is machine-generated.

Task specific dystonia (TSD) rehabilitation interventions, including massage, instrument modifications, and ultrasound therapy, offer patients perceived symptom improvement. These therapies aid in managing daily activities affected by musicians' dystonia and writer's dystonia.

Keywords:
Hand therapyMusicians’ dystoniaRehabilitation therapiesTask specific dystoniaWriters’ dystonia

More Related Videos

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
10:05

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Published on: January 27, 2018

9.9K
Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease
05:51

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

Published on: October 14, 2021

4.1K

Related Experiment Videos

Last Updated: Nov 5, 2025

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia
10:41

Implantation of Osmotic Pumps and Induction of Stress to Establish a Symptomatic, Pharmacological Mouse Model for DYT/PARK-ATP1A3 Dystonia

Published on: September 12, 2020

7.6K
Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia
10:05

Measurement & Analysis of the Temporal Discrimination Threshold Applied to Cervical Dystonia

Published on: January 27, 2018

9.9K
Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease
05:51

Induction and Assessment of Levodopa-induced Dyskinesias in a Rat Model of Parkinson's Disease

Published on: October 14, 2021

4.1K

Area of Science:

  • Neurology
  • Rehabilitation Medicine
  • Occupational Therapy

Background:

  • Task specific dystonia (TSD) is a neurological movement disorder with limited treatment options and no known cure.
  • Rehabilitative therapy outcomes from the patient's perspective for TSD are under-researched.

Purpose of the Study:

  • To explore patient-utilized interventions for task specific dystonia (TSD), specifically musicians' dystonia (MD) and writer's dystonia (WD).
  • To assess the perceived effectiveness of these interventions in treating and managing TSD symptoms.
  • To investigate the impact of TSD on daily and task-specific performance and potential causes.

Main Methods:

  • A descriptive survey was administered to 95 patients diagnosed with TSD treated at a private hand therapy unit.
  • The online survey collected data on personal information, general medical history, dystonia history, and treatment history.
  • Invitations were sent to 105 patients, achieving a 90% response rate.

Main Results:

  • Significant associations were found between TSD development and technique changes (P < .001) across both MD and WD groups.
  • Massage (P < .043), instrument modifications (P < .002), and ultrasound therapy (P < .013) were perceived as the most effective treatments.
  • All participants reported that their daily activities were affected by TSD.

Conclusions:

  • Rehabilitation interventions are perceived by individuals with TSD to be effective in enhancing symptom management.
  • Massage, instrument modifications, and ultrasound therapy are identified as key interventions for TSD management.
  • These findings provide evidence supporting the inclusion of specific rehabilitative therapies in TSD treatment plans.