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Updated: Nov 5, 2025

The Replica Set Method: A High-throughput Approach to Quantitatively Measure Caenorhabditis elegans Lifespan
Published on: June 29, 2018
How best to quantify replication success? A simulation study on the comparison of replication success metrics
Jasmine Muradchanian1, Rink Hoekstra1, Henk Kiers1
1Behavioural and Social Sciences, University of Groningen, The Netherlands.
Abstract:
To overcome the frequently debated crisis of confidence, replicating studies is becoming increasingly more common. Multiple frequentist and Bayesian measures have been proposed to evaluate whether a replication is successful, but little is known about which method best captures replication success. This study is one of the first attempts to compare a number of quantitative measures of replication success with respect to their ability to draw the correct inference when the underlying truth is known, while taking publication bias into account. Our results show that Bayesian metrics seem to slightly outperform frequentist metrics across the board. Generally, meta-analytic approaches seem to slightly outperform metrics that evaluate single studies, except in the scenario of extreme publication bias, where this pattern reverses.
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