CAR T-Cell Therapy: Updates in Nursing Management.

Area of Science:

• Oncology
• Immunotherapy
• Hematology

Background:

• Chimeric antigen receptor (CAR) T-cell therapy is a rapidly advancing treatment for blood cancers.
• This therapy necessitates specialized nursing expertise and continuous education.
• Existing nursing protocols may not fully address the unique complexities of CAR T-cell treatments.

Purpose of the Study:

• To provide updated guidance on the nursing management of CAR T-cell therapies in adult patients.
• To highlight the distinct challenges associated with CAR T-cell therapy compared to conventional chemotherapy.
• To emphasize the critical role of oncology and intensive care unit (ICU) nurses in patient care.

Main Methods:

• A comprehensive literature review was performed.
• Included sources comprised peer-reviewed articles and official pharmaceutical drug labels.
• Focus was placed on nursing management strategies and patient care considerations.

Main Results:

• CAR T-cell therapy presents unique nursing management challenges.
• Specialized knowledge is essential for nurses caring for patients undergoing this treatment.
• Continuous professional development is crucial for oncology and ICU nurses.

Conclusions:

• Nurses require updated knowledge and skills to effectively manage patients receiving CAR T-cell therapy.
• Proactive nursing care is vital to address the specific toxicities and complications of CAR T-cell treatments.
• Enhanced training and resources are needed for healthcare professionals involved in CAR T-cell therapy.