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Drug Dosing: Geriatric Patients01:15

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Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
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Pharmacodynamics in Geriatric Patients: Effects of Age01:27

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Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
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Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

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Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
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In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
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Oral Health Assessment by Lay Personnel for Older Adults
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Geriatric Syndrome Screening: Implementing an Evidence-Based Process in Hospitalized Older Adults With Cancer.

Sherry L Rafters1, Joan Schleper1, Nancy Lean1

  • 1Torrance Memorial Medical Center.

Clinical Journal of Oncology Nursing
|May 21, 2021
PubMed
Summary

Oncology nurses can screen older cancer patients for geriatric syndromes using the SPICES tool. Most patients experienced multiple issues, highlighting the need for early recognition and intervention.

Keywords:
acute carecancerevidence-based practicegeriatric syndromes

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Area of Science:

  • Geriatric Medicine
  • Oncology Nursing
  • Evidence-Based Practice

Background:

  • Geriatric syndromes significantly impact older adults with cancer.
  • Oncology nurses are crucial for early identification of these syndromes.
  • Timely recognition facilitates treatment adherence and decision-making.

Purpose of the Study:

  • To implement a nursing-led screening process for geriatric syndromes in hospitalized older cancer patients.
  • To determine the types and frequency of geriatric syndromes encountered.
  • To evaluate the feasibility of using the SPICES tool in this population.

Main Methods:

  • Nurses received training on the SPICES (Sleep disorders, Problems with eating or feeding, Incontinence, Confusion, Evidence of falls, Skin breakdown) tool.
  • Screening was conducted for geriatric syndromes among hospitalized older adult cancer patients.
  • Electronic health records were utilized for documentation and patient profiling.

Main Results:

  • Staff nurses demonstrated capability in leading evidence-based practice initiatives.
  • Adherence to the SPICES screening protocol was 47%.
  • Approximately 80% of patients presented with two or more geriatric syndromes.

Conclusions:

  • The SPICES tool can be effectively implemented by oncology nurses to screen for geriatric syndromes.
  • A high prevalence of multiple geriatric syndromes was observed in older cancer patients.
  • Nursing-sensitive interventions are essential for managing geriatric syndromes in this population.