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Cervicogenic headache. Pupillometric findings.

T A Fredriksen1, M M Wysocka-Bakowska, A Bogucki

  • 1Department of Neurosurgery, Trondheim University Hospital, Norway.

Cephalalgia : an International Journal of Headache
|June 1, 1988
PubMed
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Pupil size in cervicogenic headache patients is smaller during pain-free periods compared to during attacks. This finding differs from cluster headaches, suggesting distinct physiological mechanisms.

Area of Science:

  • Neurology
  • Ophthalmology

Background:

  • Cervicogenic headache is a disabling condition often misdiagnosed.
  • Pupillary abnormalities are observed in some headache disorders, like cluster headache.

Purpose of the Study:

  • To investigate pupillary function in patients with cervicogenic headache.
  • To compare pupillary responses in cervicogenic headache with those in cluster headache.

Main Methods:

  • Pupillary diameter was measured using a pupillometer in 11 female patients with cervicogenic headache.
  • Measurements were taken in basal state and after topical administration of tyramine, phenylephrine, and hydroxyamphetamine.
  • A control group of 26 age-matched women was included for comparison.

Main Results:

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  • Pupils were smaller in the asymptomatic period of cervicogenic headache patients compared to during pain attacks and controls.
  • No significant difference in anisocoria was found between patients and controls.
  • Drug-induced mydriasis was symmetrical in both groups, unlike the asymmetric response seen in cluster headache.

Conclusions:

  • Cervicogenic headache exhibits distinct pupillary characteristics compared to cluster headache.
  • Pupil size variations may help differentiate between cervicogenic and cluster headaches.