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Breaking the therapeutic ceiling in drug development in ulcerative colitis

Dahham Alsoud1, Bram Verstockt2, Claudio Fiocchi3

  • 1Translational Research in Gastrointestinal Disorders, Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium.

The Lancet. Gastroenterology & Hepatology
|May 21, 2021
PubMed
Summary

New ulcerative colitis (UC) therapies offer modest remission rates, hitting a therapeutic ceiling. This review critically appraises current UC treatment limits and suggests novel drug development strategies for improved patient outcomes.

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