Related Experiment Video
Updated: Nov 4, 2025
06:53
Modeling Primary Bone Tumors and Bone Metastasis with Solid Tumor Graft Implantation into Bone
Published on: September 9, 2020
3.0K
[Osteoblastoma with atypical presentation in cuboid bone].
L F Moreno-Hoyos1, J Strassburger-Weidmann2, V Castillo-Anaya1
1Ortopedia y Traumatología, Hospital Ángeles Mocel. Ciudad de México. México.
Acta Ortopedica Mexicana
|May 21, 2021
Summary
Osteoblastoma, a rare bone tumor, can exceptionally present in the foot's cuboid bone. This case highlights successful surgical treatment and the importance of considering rare presentations in diagnosis.
Area of Science:
- Orthopedic Oncology
- Skeletal Tumors
- Bone Neoplasms
Background:
- Osteoblastoma is a rare, benign but aggressive osteoblastic tumor.
- Typically found in the spine and sacrum, cuboid location is exceptionally rare.
Observation:
- A 50-year-old male presented with foot pain and swelling due to a cuboid lesion.
- Imaging revealed a hypervascular, multilobed lesion with irregular borders.
- Biopsy confirmed the tumor, classified as Enneking 2.
Findings:
- The patient underwent tumor resection, cryotherapy, and bone grafting.
- Post-surgical follow-up showed complete tumor resolution and asymptomatic recovery at three years.
- This demonstrates the efficacy of aggressive surgical management for rare osteoblastoma presentations.
Implications:
- Osteoblastoma must be considered in the differential diagnosis of cuboid bone lesions, despite its rarity.
- Comprehensive radiographic and histopathological evaluation is crucial for accurate diagnosis and treatment planning.
- This case underscores the importance of considering unusual tumor locations for effective patient management.
Related Concept Videos
01:27Compact Bone
14.7K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
14.7K
01:18Classification of Bones
8.6K
The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
8.6K
01:10Bones of the Lower Limb: Tibia and Fibula
6.9K
The tibia is the main weight-bearing bone of the lower leg. It is larger than the fibula with which it is paired. The tibia is also the second longest bone in the body and is located right below the skin. The proximal end of the tibia forms the medial and the lateral condyle, which articulates with the condyles of the femur to form the knee joint. Between the articulating surfaces is the irregular elevated area known as the intercondylar eminence that serves as the inferior attachment point for...
6.9K
01:17Gross Anatomy of Bone
7.8K
The two main features of a long bone are the diaphysis and the epiphysis.
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in...
The diaphysis is the tubular shaft that runs between the proximal and distal ends of the bone. The walls of the diaphysis are composed of dense and hard compact bone made of numerous osteons — the functional unit of the compact bone. The hollow region in the diaphysis is called the medullary cavity, which harbors the bone marrow. In infants and children, this marrow cavity is filled with red marrow, whereas in...
7.8K
01:31Osteoclasts in Bone Remodeling
3.5K
Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during...
3.5K
01:24Bone Formation by Endochondral Ossification
7.0K
Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
7.0K