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Updated: Nov 4, 2025

Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes
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Generation of Integration-free Human Induced Pluripotent Stem Cells Using Hair-derived Keratinocytes

Published on: August 20, 2015

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Reprogramming oral epithelial keratinocytes into a pluripotent phenotype for tissue regeneration.

Fayrouz Bazina1,2, Sabine M Brouxhon3, Stephanos Kyrkanides4

  • 1Ph.D. Program in Oral Biology and Pathology, School of Dental Medicine, Stony Brook University, Stony Brook, New York, USA.

Clinical and Experimental Dental Research
|May 22, 2021
PubMed
Summary

Researchers reprogrammed adult oral keratinocytes into pluripotent stem cells using TGF-β1. This breakthrough offers a potential source for regenerative dentistry applications.

Keywords:
TGFβdedifferentiationoral epitheliumstemness

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