Related Experiment Video
Updated: Aug 5, 2026

Intraductal Injection of LPS as a Mouse Model of Mastitis: Signaling Visualized via an NF-κB Reporter Transgenic
Published on: September 4, 2012
Studies on gangrenous mastitis in goats
M T Abu-Samra1, S M Elsanousi, M A Abdalla
1Department of Medicine, Faculty of Veterinary Science, University of Khartoum, Sudan.
Abstract:
One hundred and fifty goats were diagnosed as having proven gangrenous mastitis. The disease was categorized into early, intermediate and late stages. Gangrenous mastitis in goats is typified by a sudden onset, dark hyperemia, and edema with progressive discoloration of the distal part of the udder. The disease affected lactating goats but not the dry ones. Coagulase positive Staphylococcus aureus was isolated from 60% of composite and half milk samples obtained from the diseased goats. The histopathological changes mainly comprised proliferation of connective tissue, thrombosis and necrosis involving a group of lobules. Treatment of the early and intermediate stages of the disease was successful through the administration of systemic and intramammary terramycin together with diuretics and topical antiseptic cream. The late stage of the disease was successfully treated only through surgery.

