Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Effect of pre-adaptation on pattern electroretinogram (P-ERG).

G Niepel¹, F Yamamoto, E Dodt

¹Max-Planck-Institute for Physiological and Clinical Research, W.G. Kerckhoff-Institute, Bad Nauheim, FRG.

Documenta Ophthalmologica. Advances in Ophthalmology

|March 1, 1988

Summary

Pre-adaptation to light or dark significantly impacts pattern electroretinogram (P-ERG) sensitivity near threshold. However, this effect diminishes at higher luminance levels, suggesting P-ERG recording conditions are crucial for accurate cone vision assessment.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Very high resolution single pass HLA genotyping using amplicon sequencing on the 454 next generation DNA sequencers: Comparison with Sanger sequencing.

Human immunology·2015

Same author

Altered expression of dermokine in skin disorders.

Journal of the European Academy of Dermatology and Venereology : JEADV·2012

Same author

Amending reduced fish-meal feeds with marine lecithin, but not soy lecithin, improves the growth of juvenile cobia and may attenuate heightened responses to stress challenge.

Journal of animal physiology and animal nutrition·2011

Same author

Blood cardioplegia serves as a bicarbonate donor to the myocardium during ischemia: effects of anoxia and hypercapnia on acid-base characteristics of blood cardioplegic solution.

European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes·2011

Same author

[Management of mediastinitis and preventions of perioperative nosocomial infection after cardiovascular surgery].

Kyobu geka. The Japanese journal of thoracic surgery·2010

Same author

[Surgical repair of extracardiac unruptured aneurysm of the sinus of Valsalva].

Kyobu geka. The Japanese journal of thoracic surgery·2008

Area of Science:

Ophthalmology
Neuroscience
Visual Psychophysics

Background:

Pattern electroretinogram (P-ERG) is a key indicator of human cone vision.
The influence of light and dark adaptation on P-ERG recording has been largely underestimated.

Purpose of the Study:

To investigate the impact of pre-exposure to darkness versus strong light on transient P-ERG.
To determine if adaptation conditions affect P-ERG amplitude and latency.

Main Methods:

Transient P-ERGs were recorded in six healthy subjects under varying pre-adaptation conditions (darkness, pattern stimulus, bright light).
A reversing checkerboard pattern was used with specific field size, check size, reversal frequency, and contrast parameters.

Main Results:

Related Experiment Videos

Amplitude/luminance functions shifted along the luminance axis post-adaptation, indicating altered sensitivity.
A 1.3 log unit sensitivity difference was observed between dark and light pre-adaptation.
P-ERG latencies (q and r components) were shorter after strong light pre-adaptation compared to darkness.

Conclusions:

Pre-adaptation has minimal effect on P-ERG at high luminance levels.
Adaptation conditions are critical and must be considered for P-ERG recordings near visual threshold.