Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

1.2K
The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
1.2K
Immunological Memory01:23

Immunological Memory

13.4K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
13.4K
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

864
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
864
Immunodeficiency Diseases01:25

Immunodeficiency Diseases

1.4K
Immunodeficiency disorders are conditions in which the immune system's ability to fight infectious disease and cancer is compromised or entirely absent. The immune system comprises a complex network of cells, tissues, and organs that work together to protect the body from potentially harmful invaders. When this system is deficient or not functioning properly, it leaves the body susceptible to infections, diseases, or other complications.
There are three main causes of immunodeficiency...
1.4K
Humoral Immune Responses01:36

Humoral Immune Responses

79.2K
Overview
79.2K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

78.4K
Overview
78.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical and Radiological Outcomes of Skip-Level Cervical Disk Arthroplasty.

Neurosurgery·2026
Same author

Increasing autophagy activity suppresses <i>Helicobacter pylori</i> infection-related gastric cancer tumorigenesis both <i>in vitro</i> and <i>in vivo</i>.

American journal of cancer research·2026
Same author

Cryosurgical cranioplasty using autologous bone for metastatic skull lesion from hepatocellular carcinoma: illustrative case.

Journal of neurosurgery. Case lessons·2026
Same author

Taiwan practical consensus for evaluation and management of small-bowel bleeding.

Journal of the Chinese Medical Association : JCMA·2026
Same author

Gut microbiota profiles by LDL-C target achievement in statin-treated patients: A cross-sectional study.

Nutrition, metabolism, and cardiovascular diseases : NMCD·2025
Same author

<i>Clostridium butyricum MIYAIRI 588</i> Reduces Colorectal Adenomatous Polyp Recurrence: A Randomized Crossover Trial.

Oncology research·2025
Same journal

Foreign body infection following Staphylococcus aureus bloodstream infection: Host risk factors and bacterial genetic characteristics.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2026
Same journal

MicroRNAs in sepsis diagnosis: A systematic review and meta-analysis toward evidence-based biomarker development.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2026
Same journal

Outcomes associated with carbapenem-sparing versus carbapenem-containing therapy for third-generation cephalosporin non-susceptible Serratia marcescens bacteremia: a retrospective cohort analysis.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2026
Same journal

Corrigendum to "Younger adults with mild-to-moderate COVID-19 exhibited more prevalent olfactory dysfunction in Taiwan" [J Microbiol Immunol Infect 54 (2021) 794-800].

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2026
Same journal

Combined Aspergillus-specific IgG and galactomannan testing optimizes diagnosis of invasive pulmonary aspergillosis in non-neutropenic patients.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2026
Same journal

Beyond the stomach: Repurposing bismuth tripotassium dicitrate as a novel strategy against multidrug-resistant Mycobacterium abscessus.

Journal of microbiology, immunology, and infection = Wei mian yu gan ran za zhi·2026
See all related articles

Related Experiment Video

Updated: Nov 4, 2025

Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays
06:03

Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays

Published on: September 20, 2024

1.5K

Immunological map in COVID-19.

Chung-Hsiang Li1, Hsin-Ying Clair Chiou2, Ming-Hong Lin3

  • 1Department of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan; Department of Pediatrics, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung, Taiwan.

Journal of Microbiology, Immunology, and Infection = Wei Mian Yu Gan Ran Za Zhi
|May 23, 2021
PubMed
Summary
This summary is machine-generated.

This study compares immunological changes in COVID-19, SARS, and MERS. Key predictors of severe COVID-19 include elevated white blood cells, low lymphocytes, and high inflammatory cytokines.

Keywords:
COVID-19ImmunePandemicPneumoniaSARS-CoV-2

More Related Videos

Author Spotlight: Unlocking Insights into the Immune Cell Landscape of Tumors
06:32

Author Spotlight: Unlocking Insights into the Immune Cell Landscape of Tumors

Published on: August 18, 2023

2.5K
Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

3.1K

Related Experiment Videos

Last Updated: Nov 4, 2025

Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays
06:03

Author Spotlight: Advancing Immune Monitoring in Critical Care Patients Using Whole Blood Assays

Published on: September 20, 2024

1.5K
Author Spotlight: Unlocking Insights into the Immune Cell Landscape of Tumors
06:32

Author Spotlight: Unlocking Insights into the Immune Cell Landscape of Tumors

Published on: August 18, 2023

2.5K
Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19
08:48

Dynamic Monitoring of Seroconversion using a Multianalyte Immunobead Assay for Covid-19

Published on: February 16, 2022

3.1K

Area of Science:

  • Immunology
  • Infectious Diseases
  • Virology

Background:

  • Coronavirus disease 2019 (COVID-19) is caused by SARS-CoV-2, sharing similarities with SARS-CoV and MERS-CoV.
  • The precise pathogenesis and immunological effects of SARS-CoV-2 remain incompletely understood.

Purpose of the Study:

  • To compare immunological changes across SARS-CoV-2, SARS-CoV, and MERS-CoV infections.
  • To identify immunological differences between severe and non-severe COVID-19 cases.
  • To explore potential immunological predictors of patient outcomes in COVID-19.

Main Methods:

  • Comparative analysis of immunological profiles.
  • Review of case series studies on COVID-19 patients.
  • Investigation of cytokine and immune cell levels.

Main Results:

  • Identified leukocytosis, neutrophilia, and lymphopenia (CD4+, CD8+ T cells) as potential indicators of poor outcomes.
  • Highlighted elevated neutrophil-to-lymphocyte ratio (NLR) and increased pro-inflammatory cytokines (IL-6, TNF-α) in severe cases.
  • Noted increased Th1 (IL-2, IFN-γ), regulatory T cell (IL-10), and Th17 (IL-17) cytokines associated with adverse outcomes.

Conclusions:

  • Specific immunological markers may predict COVID-19 severity and patient outcomes.
  • Further research is needed to establish a detailed immunological map for improved diagnosis and precision medicine.
  • Understanding these immunological differences is crucial for developing targeted treatments.