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A Randomized Trial of Home Blood-Pressure Reduction by Alcohol Guidance During Outpatient Visits: OSAKE Study
Mai Kabayama1, Yuya Akagi1, Naoko Wada1
1Department of Health Sciences, Osaka University Graduate School of Medicine, Suita, Japan.
Insights
Nurse-led alcohol guidance effectively controlled home blood pressure (HBP) in hypertensive men. This intervention significantly reduced HBP and alcohol consumption in male outpatients during the study.
Area of Science:
- Cardiology
- Public Health
- Nursing
Background:
- Hypertension is a prevalent condition, often exacerbated by excessive alcohol consumption.
- Managing home blood pressure (HBP) is crucial for hypertensive patients.
- Male patients with hypertension frequently present with excessive alcohol intake, complicating treatment.
Purpose of the Study:
- To evaluate the effectiveness of nurse-led alcohol guidance in controlling morning HBP.
- To assess the impact of this intervention on alcohol consumption in male hypertensive outpatients.
Main Methods:
- A randomized trial involving 53 male hypertensive outpatients with excessive alcohol intake (≥210 g/week).
- Patients were assigned to either a nurse-led alcohol guidance intervention or a control group.
- Primary outcomes measured were HBP levels over 5 consecutive days at 6 months and alcohol consumption.
Main Results:
- The intervention group showed significantly lower mean HBP (131/82 mm Hg) compared to the control group (145/87 mm Hg) at 6 months (SBP P<0.001).
- A greater proportion of participants in the intervention group achieved target HBP (<135/85 mm Hg): 55.6% vs. 16.7% (P = 0.004).
- Alcohol consumption was significantly reduced in the intervention group (256 g/w) versus the control group (413 g/w) (P = 0.020).
Conclusions:
- Nurse-led alcohol guidance is an effective strategy for controlling HBP in male hypertensive patients.
- This intervention demonstrates success in outpatient settings for managing both blood pressure and alcohol intake.
Background:
To evaluate the effectiveness of the nurse-led alcohol guidance to control home blood pressure (HBP) in the morning among male patients with hypertension during outpatient visits.
Methods:
We enrolled 53 male patients with an HBP of ≥135/85 mm Hg with excessive drinking (alcohol ≥210 g/week or ≥60 g/day habitually) among outpatients in a randomized trial. Patients were assigned to a nurse-led alcohol guidance intervention or to the control. The primary outcomes were the mean HBP of 5 consecutive days at 6 months and alcohol consumption.
Results:
Twenty-eight and 25 patients were randomized to intervention and control groups, respectively (mean age; 62.7 years old and 64.5, respectively). At baseline, the groups were well balanced across most characteristics. At 6 months, the mean HBP was 131/82 mm Hg in the intervention group vs. 145/87 mm Hg in the control group (SBP <0.001, DBP = 0.09). An HBP level of less than 135/85 mm Hg was achieved among 55.6% of the participants in the intervention group vs. 16.7% in the control group (P = 0.004). The alcohol consumption at 6 months was 256 ± 206 g/w vs. 413 ± 260 g/w, respectively (P = 0.020).
Conclusions:
We confirmed the effectiveness of the nurse-led alcohol guidance to control the HBP in male patients with hypertension during outpatient visits.
Public Trials Registry Number:
UMIN000017454 (UMIN Clinical Trials Registry).
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