Related Experiment Video
Updated: Nov 4, 2025
09:01
Treatment of Ankle Osteoarthritis with Total Ankle Replacement Through a Lateral Transfibular Approach
Published on: January 24, 2018
12.0K
Two-Year Outcomes After Total Ankle Replacement With a Novel Fixed-Bearing Implant
Sahil Kooner1, Shahin Kayum2, Ellie B Pinsker2
1University of Calgary, Calgary, Alberta, Canada.
Foot & Ankle International
|May 24, 2021
Summary
The Integra Cadence total ankle replacement (TAR) shows excellent short-term results, significantly improving patient pain and function. This fourth-generation implant achieved high survivorship and accurate alignment in early clinical use.
Area of Science:
- Orthopedic surgery
- Biomedical engineering
Background:
- The Integra Cadence total ankle replacement (TAR) is a fourth-generation, fixed-bearing implant introduced in June 2016.
- It features an anatomic design and requires minimal bone resection during implantation.
Purpose of the Study:
- To evaluate the short-term clinical and radiographic outcomes of the Integra Cadence TAR.
- To assess patient-reported outcomes, implant alignment, and complication rates.
Main Methods:
- A prospective case series of 69 consecutive patients undergoing TAR between June 2016 and November 2017.
- Primary outcome: Ankle Osteoarthritis Scale (AOS). Secondary outcomes: SF-36 scores, radiographic alignment, complications, reoperations, and revisions.
- Study design: Level IV evidence, case series.
Main Results:
- Significant postoperative improvements in AOS pain (17.8 points) and disability (22.0 points) scores (P < .001).
- SF-36 physical component summary score improved by 10.4 points (P < .001).
- 97% of patients achieved neutral coronal alignment; 100% 2-year implant survivorship with no revisions. Fibrous ingrowth in 26.1% did not negatively impact outcomes.
Conclusions:
- The Integra Cadence TAR system demonstrates excellent early clinical and radiographic outcomes.
- The prosthesis facilitates accurate implantation, deformity correction, and improved patient physical health status.
- Further long-term prospective studies are warranted to confirm these promising early results.
