[SARS-CoV-2 infection: Available data on 15th April 2021]

Area of Science:

• Pulmonology and Infectious Diseases
• Virology and Immunology
• Epidemiology

Background:

• Pulmonologists have been central to managing COVID-19 since January 2020.
• Numerous drugs have been investigated for SARS-CoV-2 treatment.
• As of April 15, 2021, only supportive care was recommended.

Purpose of the Study:

• To present the state of knowledge on COVID-19 in the acute phase.
• To cover virological, immunological, epidemiological, and therapeutic data.
• To provide an update as of April 15, 2021.

Main Methods:

• Review of available scientific literature and clinical trial data.
• Synthesis of virological, immunological, and epidemiological findings.
• Analysis of current therapeutic strategies and ongoing research.

Main Results:

• The standard of care for acute COVID-19 involves symptomatic management.
• Oxygen therapy, thromboprophylaxis, and corticosteroids are key components of current management.
• No specific antiviral therapy is currently recommended for SARS-CoV-2.

Conclusions:

• Clinical trials for COVID-19 treatments are actively progressing.
• Patient participation in clinical trials should be encouraged.
• Research needs to be structured to facilitate the completion of ongoing studies.