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COVID-19 and cardiovascular complications - preliminary results of the LATE-COVID study

Joanna Lewek1,2, Izabela Jatczak-Pawlik1,3, Marek Maciejewski2

  • 1Department of Hypertension, Chair of Nephrology and Hypertension, Medical University of Lodz, Poland.

Archives of Medical Science : AMS
|May 24, 2021
PubMed

Insights

Post-COVID-19 cardiovascular complications can be severe, particularly in patients with diabetes. Key indicators of severity include reduced ejection fraction and elevated C-reactive protein and troponin levels.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Internal Medicine

Background:

  • Coronavirus disease 2019 (COVID-19) is known to affect multiple organs, leading to various complications.
  • Cardiovascular issues are among the significant post-COVID-19 complications observed in patients.

Purpose of the Study:

  • To investigate the clinical characteristics and outcomes of cardiovascular complications following COVID-19.
  • To identify factors associated with the severity of these post-COVID-19 cardiovascular issues.

Main Methods:

  • Analysis of 51 patients admitted for potential cardiovascular complications post-COVID-19.
  • Data collection included clinical information, laboratory tests, echocardiography, and 24-hour ECG monitoring.

Main Results:

  • Severe cardiovascular complications occurred in 27.5% of hospitalized patients, typically 1-4 months after recovery.
  • Patients with severe complications showed higher rates of diabetes, decreased ejection fraction, elevated heart rate, C-reactive protein, and troponin T.
  • Dyspnea and exercise intolerance were more prevalent in those with severe complications.

Conclusions:

  • Diabetes, elevated C-reactive protein (CRP), troponin levels, and reduced left ventricular ejection fraction are linked to severe cardiovascular complications after COVID-19.
  • Heart rate variability parameters also correlate with the severity of post-COVID-19 cardiovascular sequelae.
Abstract

Keywords:
COVID-19autonomic dysregulationcardiovascular complicationsdecrease in left ventricular ejection fractionmyocarditis

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