Cardiac Rhabdomyoma in Adult

Area of Science:

• Cardiology
• Genetics
• Oncology

Background:

• Cardiac rhabdomyoma is a benign heart tumor and the primary cardiac manifestation of tuberous sclerosis complex (TSC).
• TSC is an autosomal dominant genetic disorder with variable multi-organ involvement.
• While common in infants, TSC-associated cardiac rhabdomyoma typically regresses spontaneously within two years.

Observation:

• A 34-year-old woman with a known diagnosis of TSC presented for cardiology evaluation.
• Cardiac rhabdomyoma was identified during her cardiology clinic visit.
• The patient was asymptomatic at the time of diagnosis.

Findings:

• Cardiac rhabdomyoma is exceptionally rare in adults, with most cases diagnosed in infancy.
• The tumor, though often asymptomatic, can cause significant cardiac issues based on its size and location.
• Potential complications include outflow/inflow tract obstruction and aberrant electrical conduction.

Implications:

• This case underscores the importance of recognizing that cardiac rhabdomyomas can persist into adulthood.
• Appropriate cardiac surveillance is crucial for adult patients with TSC and cardiac rhabdomyomas.
• Early detection and monitoring can help manage potential cardiac complications.