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Microorganisms and cardiovascular diseases: importance of gut bacteria

Rashed Noor1, Adiba Naz1, Syeda Muntaka Maniha1

  • 1Department of Life Sciences (DLS), School of Environment and Life Sciences (SELS), Independent University, Bangladesh (IUB), 1212 Dhaka, Bangladesh.

Frontiers in Bioscience (Landmark Edition)
|May 24, 2021
PubMed

Insights

Gut microbes influence heart health, potentially causing cardiovascular diseases. Understanding this gut-heart axis is crucial for public health, especially in developing nations.

Area of Science:

  • Microbiology
  • Cardiology
  • Public Health

Background:

  • Cardiovascular diseases (CVDs) are a major global health concern.
  • While non-infectious causes are known, microbial involvement in heart disease is often overlooked.
  • Gut microorganisms play a significant role in various bodily functions, including immunity and metabolism.

Purpose of the Study:

  • To review the role of gut microflora in the development of heart diseases.
  • To highlight the importance of the gut-heart axis in cardiovascular health.
  • To raise public awareness regarding microbial contributions to heart conditions.

Main Methods:

  • Literature review focusing on the gut microbiome and cardiovascular diseases.
  • Analysis of studies investigating the impact of gut microbial composition on cardiac function.
  • Synthesis of information on mechanisms linking gut dysbiosis to heart ailments.

Main Results:

  • Alterations in gut microbial composition can lead to cardiac membrane impairment.
  • Gut dysbiosis is associated with metabolic dysfunction within the heart.
  • Imbalances in gut microbiota can negatively affect immune cell function, impacting cardiovascular health.

Conclusions:

  • The gut microbiome significantly influences the onset and progression of heart diseases.
  • Understanding the gut-heart axis is vital for developing novel strategies for CVD prevention and treatment.
  • Public health initiatives should address the role of gut microorganisms in cardiovascular health, particularly in underserved regions.

Keywords:
Cardiovascular diseasesGut bacteriaImmune cellsMicroorganismsPublic healthReview

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