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Updated: Nov 4, 2025

Quantitative Autonomic Testing
Published on: July 19, 2011
[FALSE POSITIVE AMBULATORY BLOOD PRESSURE MONITORING: CHALLENGES IN ACCURATE DIAGNOSIS OF MASKED UNCONTROLLED
Temira Feinsilver1, Howard Tandeter1
1Department of Family Medicine and Siaal Research Center for Family Medicine and Primary Care, Division of Community Health, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel.
Masked uncontrolled hypertension (MUCH) can be misdiagnosed. This study highlights how stress can cause false-positive ambulatory blood pressure monitoring (ABPM) results, emphasizing the need for pre-test stress assessment to improve diagnostic accuracy.
Area of Science:
- Cardiology
- Hypertension Management
- Diagnostic Accuracy
Background:
- Masked uncontrolled hypertension (MUCH) is underdiagnosed but linked to severe complications.
- Ambulatory blood pressure monitoring (ABPM) is the gold standard for diagnosing hypertension, particularly MUCH.
- Limitations of ABPM, including false positives, are rarely discussed.
Purpose of the Study:
- To report a case of false-positive ABPM due to situational stress.
- To propose a strategy for improving ABPM accuracy by assessing patient stress levels before testing.
Main Methods:
- A case report detailing ABPM results.
- Comparison of ABPM readings obtained during stressful versus non-stressful conditions.
- Literature review on ABPM advantages and limitations.
Main Results:
- A patient initially presented with a positive ABPM result.
- Repeat ABPM in a non-stressful setting yielded normal blood pressure readings.
- This suggests stress can induce false-positive ABPM findings.
Conclusions:
- Situational stress can lead to false-positive ABPM results.
- Routine pre-test assessment for stressful situations is recommended.
- Implementing this strategy can enhance ABPM accuracy and prevent misdiagnosis.
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