Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of implementation of an EHR-based sepsis alert system with sepsis-associated acute kidney injury.

The American journal of emergency medicine·2026
Same author

Hypophosphatemia During Kidney Replacement Therapy and Ventilator-Free Days: A Post Hoc Analysis of the STARRT-AKI Trial.

American journal of kidney diseases : the official journal of the National Kidney Foundation·2026
Same author

Four-organ SOFA score as a potential tool to triage use of continuous kidney replacement therapy in COVID-19 patients with acute kidney injury: a retrospective two-center study.

Renal failure·2026
Same author

Agomelatine normalizes region-specific, diurnal mGluR5 dysregulation in a chronic mild stress rat model of depression.

Progress in neuro-psychopharmacology & biological psychiatry·2025
Same author

Association of platelet trajectory patterns with in-hospital mortality in critically ill adults with acute kidney injury receiving continuous renal replacement therapy.

BMC nephrology·2025
Same author

Change in platelet and leukocyte counts and hospital mortality in adults with acute kidney injury receiving continuous renal replacement therapy.

Scientific reports·2025

Related Experiment Video

Updated: Nov 4, 2025

A Within-Subject Experimental Design using an Object Location Task in Rats
09:28

A Within-Subject Experimental Design using an Object Location Task in Rats

Published on: May 6, 2021

4.8K

A Within-Subject Experimental Design using an Object Location Task in Rats.

Gülberk Bayraktar1, Kristoffer Højgaard2, Luc Nijssen3

  • 1Danish Research Institute of Translational Neuroscience (DANDRITE), Department of Biomedicine, Aarhus University; Universitätsklinikum Würzburg, Institut für Klinische Neurobiologie.

Journal of Visualized Experiments : Jove
|May 24, 2021
PubMed
Summary
This summary is machine-generated.

This study details a robust protocol for the object location task in rodents, enhancing spatial memory research. The method allows for repeated testing to improve statistical power and experimental efficiency.

More Related Videos

Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget
05:57

Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget

Published on: November 20, 2018

57.5K
A Fully Automated Rodent Conditioning Protocol for Sensorimotor Integration and Cognitive Control Experiments
09:43

A Fully Automated Rodent Conditioning Protocol for Sensorimotor Integration and Cognitive Control Experiments

Published on: April 15, 2014

10.8K

Related Experiment Videos

Last Updated: Nov 4, 2025

A Within-Subject Experimental Design using an Object Location Task in Rats
09:28

A Within-Subject Experimental Design using an Object Location Task in Rats

Published on: May 6, 2021

4.8K
Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget
05:57

Novel Object Recognition and Object Location Behavioral Testing in Mice on a Budget

Published on: November 20, 2018

57.5K
A Fully Automated Rodent Conditioning Protocol for Sensorimotor Integration and Cognitive Control Experiments
09:43

A Fully Automated Rodent Conditioning Protocol for Sensorimotor Integration and Cognitive Control Experiments

Published on: April 15, 2014

10.8K

Area of Science:

  • Neuroscience
  • Behavioral Neuroscience
  • Cognitive Neuroscience

Background:

  • Object place recognition is a key method for studying spatial memory in rodents.
  • The object location task is based on object place recognition memory.

Purpose of the Study:

  • To provide an extensive protocol for establishing an object location task.
  • To enable the study of short- and long-term spatial memories with varying strengths.
  • To facilitate memory-inhibiting or -enhancing manipulations.

Main Methods:

  • The protocol allows for up to four repetitions of the object location task within the same cohort of rats.
  • Both weak and strong encoding protocols can be implemented.
  • Counterbalancing is used for test repetition to enable within-subject comparisons.

Main Results:

  • Repetition of the object location task reduces variability between rats, increasing statistical power.
  • This method is particularly useful for experiments with high individual behavioral variation.
  • The repeated task design enhances the efficiency of studies involving surgical procedures.

Conclusions:

  • The detailed protocol for the repeated object location task offers a powerful tool for spatial memory research in rodents.
  • This approach increases experimental efficiency and statistical robustness.
  • The protocol supports the investigation of memory mechanisms and the development of therapeutic strategies.