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Ventricular late potentials in normal subjects.

N C Flowers1, A C Wylds

  • 1Department of Medicine, Medical College of Georgia, Augusta.

Herz
|June 1, 1988
PubMed
Summary
This summary is machine-generated.

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Late potentials, indicators of potential heart rhythm issues, were found in 4% of healthy individuals. While often a false positive, they may signal underlying cardiac pathology in some cases.

Area of Science:

  • Cardiology
  • Electrophysiology

Background:

  • Low-amplitude late potentials in ventricular activation are investigated for predicting sustained ventricular tachyarrhythmias.
  • These signals are typically absent in individuals without arrhythmias and in healthy subjects.

Purpose of the Study:

  • To determine the incidence of late potentials in a cohort of healthy individuals.
  • To compare findings with previously studied normal subjects using similar methodologies.

Main Methods:

  • Studied 67 healthy subjects with no history or ECG evidence of cardiac disease.
  • Analyzed vectormagnitude complexes and compared measured indices with established data.

Main Results:

  • Three subjects (4%) exhibited abnormal late potentials, with vectormagnitude complexes resembling those in patients with ventricular tachycardia post-myocardial infarction.

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  • Indices were compared with those from other studies using similar analytical techniques and equipment.

    • Conclusions:

    • The incidence of late potentials in normal subjects is very low.
    • Abnormal findings in healthy individuals may represent false positives due to recording or analytical techniques.
    • In some instances, late potentials in seemingly healthy individuals could indicate underlying structural cardiac pathology.