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Ulcerative ileojejunitis associated with pulmonary fibrosis and polymyositis
M O Coupe1, M L Barnard, G Stamp
1Department of Gastroenterology, Royal Postgraduate Medical School, Hammersmith Hospital, London, England.
Hepato-Gastroenterology
|June 1, 1988
Summary
A rare case of ulcerative ileojejunitis developed in a patient with celiac disease. The condition, along with polymyositis and alveolitis, responded to corticosteroid treatment, suggesting an autoimmune link.
Area of Science:
- Gastroenterology and Immunology
- Autoimmune Diseases
Background:
- Celiac disease is an autoimmune disorder triggered by gluten.
- Ulcerative ileojejunitis is a rare inflammatory condition affecting the small intestine.
Observation:
- A patient with a history of celiac disease developed ulcerative ileojejunitis.
- The patient subsequently developed polymyositis and inflammatory alveolitis.
Findings:
- Long-term remission of ulcerative ileojejunitis was achieved with corticosteroids.
- Polymyositis and alveolitis also responded to increased corticosteroid dosage (prednisolone).
Implications:
- This case highlights a potential autoimmune connection between celiac disease, ulcerative ileojejunitis, polymyositis, and fibrosing alveolitis.
- Corticosteroids may be a viable treatment option for this complex autoimmune presentation.