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High-frequency High-resolution Echocardiography: First Evidence on Non-invasive Repeated Measure of Myocardial Strain, Contractility, and Mitral Regurgitation in the Ischemia-reperfused Murine Heart
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Prognostic value of right ventricular strain pattern on ECG in COVID-19 patients

Hasan Ali Barman1, Adem Atici2, Irfan Sahin3

  • 1Istanbul University-Cerrahpaşa, Institute of Cardiology, Department of Cardiology, Istanbul,Turkey; University of Health Sciences, Okmeydani Training and Research Hospital, Department of Cardiology, Istanbul, Turkey.

The American Journal of Emergency Medicine
|May 24, 2021
PubMed

Insights

Right ventricular strain, identified by ECG, is a significant predictor of mortality in COVID-19 patients. This finding highlights the importance of ECG in assessing COVID-19 prognosis and patient outcomes.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Critical Care Medicine

Background:

  • The ongoing COVID-19 pandemic continues to cause significant morbidity and mortality worldwide.
  • Assessing prognostic factors in hospitalized COVID-19 patients is crucial for timely intervention and improved outcomes.

Purpose of the Study:

  • To investigate the prognostic value of right ventricular (RV) strain, as detected by electrocardiogram (ECG), in predicting mortality among patients hospitalized with COVID-19.

Main Methods:

  • A cohort of 324 adult COVID-19 patients admitted between April 1-30 was analyzed.
  • Right ventricular strain was defined by specific ECG findings (RBBB, T-wave changes, S1Q3T3).
  • Multivariable Cox regression analysis was used to identify independent predictors of in-hospital mortality.

Main Results:

  • Twenty-nine percent of patients exhibited RV strain on ECG.
  • In-hospital mortality was observed in 20% of the study cohort.
  • RV strain on ECG, along with high-sensitivity troponin I, d-dimer, and age, independently predicted mortality (OR: 4.385, p < 0.001).

Conclusions:

  • The presence of a right ventricular strain pattern on ECG is significantly associated with in-hospital mortality in COVID-19 patients.
  • ECG-based RV strain assessment can serve as a valuable prognostic tool in the management of COVID-19.
  • Early identification of RV strain may aid clinicians in stratifying risk and optimizing care for critically ill COVID-19 patients.
Abstract

Keywords:
COVID-19ElectrocardiographyPrognosisRight ventricular strain

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