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Isolation of a chemotactic protein for neutrophils from human ovarian follicular fluid
W K Seow1, Y H Thong, M J Waters
1Department of Child Health, University of Queensland, Mater Children's Hospital, South Brisbane, Australia.
Abstract:
Human follicular fluid was found to contain a factor chemotactic for human neutrophils. This chemotactic activity was shown to be heat labile and trypsin sensitive. Gel permeation chromatography experiments indicate that the chemotactic protein has an approximate molecular weight of 100 kd. Isoelectric focussing suggests an isoelectric point for this protein of around 5.8. The biologic and clinical significance of this apparently unique chemotactic protein remains to be determined.