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A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Recent advances in bionanomaterials for liver cancer diagnosis and treatment
Mohammed Mehadi Hassan Chowdhury1, Christiancel Joseph J Salazar2, Md Nurunnabi3
1School of Medicine, Faculty of Health, Deakin University, 75 Pigdons Road, Waurnponds, Vic-3216, Australia and Department of Microbiology, Noakhali Science and Technology University, Noakhali-3814, Bangladesh.
Abstract:
According to the World Health Organization, liver cancer is the fourth leading cause of cancer associated with death worldwide. It demands effective treatment and diagnostic strategies to hinder its recurrence, complexities, aggressive metastasis and late diagnosis. With recent progress in nanotechnology, several nanoparticle-based diagnostic and therapeutic modalities have entered into clinical trials. With further developments in nanoparticle mediated liver cancer diagnosis and treatment, the approach holds promise for improved clinical liver cancer management. In this review, we discuss the key advances in nanoparticles that have potential for liver cancer diagnosis and treatment. We also discuss the potential of nanoparticles to overcome the limitations of existing therapeutic modalities.
Insights
Nanotechnology offers promising solutions for liver cancer, enhancing early diagnosis and treatment. Nanoparticles show potential to overcome current limitations in managing this deadly disease.
Area of Science:
- Oncology
- Nanotechnology
- Biomedical Engineering
Background:
- Liver cancer is a major global health concern, ranking as the fourth leading cause of cancer death worldwide.
- Current treatment and diagnostic strategies face challenges including recurrence, metastasis, and late diagnosis.
Purpose of the Study:
- To review key advances in nanoparticle applications for liver cancer diagnosis and treatment.
- To explore the potential of nanotechnology in overcoming existing therapeutic limitations for liver cancer.
Main Methods:
- Review of recent scientific literature on nanoparticle-based diagnostic and therapeutic modalities for liver cancer.
- Analysis of clinical trial progress and future potential of nanotechnology in oncology.
Main Results:
- Nanoparticle-based approaches are advancing rapidly, with several entering clinical trials.
- Nanotechnology demonstrates significant promise for improving early detection and targeted treatment of liver cancer.
Conclusions:
- Nanoparticles represent a promising frontier in liver cancer management.
- Further development in nanoparticle-mediated strategies could revolutionize clinical outcomes for liver cancer patients.
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