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Author Spotlight: Integrating Ultrasound Imaging with Biochemical Markers for Thyroid Disease Diagnosis
Published on: February 9, 2024
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Thyroid and heart, a clinically relevant relationship
G Corona1, L Croce2,3,4, C Sparano5
1Endocrinology Unit, Medical Department, Maggiore-Bellaria Hospital, Azienda-Usl Bologna, Bologna, Italy.
Journal of Endocrinological Investigation
|May 25, 2021
Summary
Thyroid disorders impact cardiovascular health, with established links for overt conditions and ongoing debate for subclinical thyroid dysfunction. This review synthesizes meta-analyses on thyroid disease and heart risks.
Area of Science:
- Endocrinology
- Cardiology
- Internal Medicine
Background:
- Thyroid disorders are common, affecting many individuals globally.
- Overt thyroid dysfunction clearly links to cardiovascular complications.
- Subclinical thyroid dysfunction's cardiovascular impact remains debated.
Purpose of the Study:
- To review recent meta-analyses on thyroid dysfunction and cardiovascular disease.
- To explore the complex relationship between thyroid imbalances and heart health.
- To summarize evidence on cardiovascular risks associated with thyroid disorders.
Main Methods:
- Systematic review of meta-analyses.
- Analysis of cardiovascular risk in overt and subclinical thyroid dysfunction.
- Stratification of data by age, TSH levels, and pre-existing cardiovascular disease.
Main Results:
- Physiopathological links between thyroid hormones and the cardiovascular system.
- Evidence from meta-analyses on cardiovascular risk in overt thyroid dysfunction.
- Evidence from meta-analyses on cardiovascular risk in subclinical thyroid dysfunction, stratified by key patient factors.
Conclusions:
- Thyroid hormone imbalances have significant cardiovascular implications.
- Cardiovascular risk varies with overt and subclinical thyroid dysfunction, influenced by patient factors.
- Therapy for subclinical thyroid disease may improve cardiovascular outcomes.
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