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Related Concept Videos

Menopause01:28

Menopause

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Menopause, a natural biological process marking the end of a woman's fertility, typically occurs between the fifth and sixth decade of life. This phase is characterized by the exhaustion of the ovarian follicle pool, leading to less responsive ovaries despite the high levels of Follicle Stimulating Hormone (FSH) and Luteinizing Hormone (LH). The consequential decrease in estrogen production results in symptoms like hot flashes, heavy sweating, headaches, hair loss, muscle pains, vaginal...
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Hormonal Regulation of the Menstrual Cycle01:22

Hormonal Regulation of the Menstrual Cycle

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The ovarian cycle regulates endometrial changes throughout a single menstrual cycle via the coordinated action of gonadotrophin-releasing hormone (GnRH) and gonadotrophins.
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...
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Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Hormonal Regulation01:40

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Hormones regulate a significant portion of digestion through activation of the neuroendocrine system. The neuroendocrine system of digestion contains many different hormones all with multiple functions that are both, directly and indirectly, involved in digestion.
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Hormonal Regulation01:33

Hormonal Regulation

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The renin-aldosterone system is an endocrine system which guides the renal absorption of water and electrolytes, thus managing blood pressure and osmoregulation. Activation of the system begins in the kidneys with a small cluster of cells adjacent to the afferent and efferent blood vessels of the renal corpuscle. As the nephrons are filtering blood, juxtaglomerular cells monitor blood pressure. If they detect a decrease in pressure, they release the hormone renin into the bloodstream.
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Regulation of Food Intake01:30

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Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
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Updated: Nov 4, 2025

Multidisciplinary Approach to Obesity Management: A Case Report
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Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

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Weight regulation in menopause.

Michael G Knight1, Chika Anekwe2, Krystilyn Washington3

  • 1Division of General Internal Medicine, Department of Medicine, The George Washington University School of Medicine and Health Sciences, Washington, DC.

Menopause (New York, N.Y.)
|May 25, 2021
PubMed
Summary
This summary is machine-generated.

Obesity significantly impacts postmenopausal women, increasing health risks. Comprehensive assessment and tailored treatments, including lifestyle changes and medical interventions, are crucial for managing obesity in this demographic.

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Area of Science:

  • Endocrinology
  • Public Health
  • Gerontology

Background:

  • Obesity is a widespread chronic disease affecting millions, with postmenopausal women experiencing higher rates of severe obesity.
  • Obesity in this population is associated with increased morbidity, mortality, and numerous related health conditions.
  • Hormonal, lifestyle, and environmental changes during menopause contribute to obesity and increase cardiometabolic disease risk.

Purpose of the Study:

  • To review the epidemiology, pathophysiology, clinical assessment, and treatment of obesity in postmenopausal women.
  • To synthesize current understanding of obesity's effects in this specific patient group.
  • To highlight the importance of effective management strategies for reducing obesity-related health risks.

Main Methods:

  • A literature review of MEDLINE database articles published between 2000 and 2020.
  • Utilized search terms including "women, obesity, menopause, aging, metabolism, weight gain, treatment of obesity, weight loss, bariatric surgery, weight loss medications, diet, physical activity, and behavior modification."
  • Focused on current evidence regarding obesity in postmenopausal women.

Main Results:

  • Obesity is a complex, chronic, and relapsing condition requiring multifaceted management.
  • Hormonal shifts during menopause, alongside lifestyle and environmental factors, contribute to weight gain and increased cardiometabolic risk.
  • Effective interventions are available to mitigate the adverse effects of obesity.

Conclusions:

  • Comprehensive assessment and tailored treatment are essential for managing obesity in postmenopausal women.
  • Implementing lifestyle, pharmacotherapeutic, and surgical interventions can significantly reduce the negative health consequences of obesity.
  • Early identification and management are key to improving outcomes for postmenopausal women with obesity.