The synthesis of 2-(functionalized methyl)-1 beta-methylcarbapenems
Related Experiment Videos
S M Schmitt1, T N Salzmann, D H Shih
1Merck Sharp and Dohme Research Laboratories, Rahway, New Jersey 07065.
The Journal of Antibiotics
|June 1, 1988
Abstract:
The synthesis of 1 beta-methylcarbapenems having a ROCH2 substituent at the 2-position is described. Their in vitro antibacterial activity and DHP-I susceptibilities are presented.