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Updated: Nov 4, 2025

Protocol for the Synthesis of Ortho-trifluoromethoxylated Aniline Derivatives
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α-[Amino(4-aminophenyl)thio]methylene-2-(trifluoromethyl)benzeneacetonitrile; Configurational equilibria in solution

Charles J McElhinny1, Anita H Lewin1, Larry Brieaddy1

  • 1Research Triangle Institute, P.O. Box 12194, Research Triangle Park, NC 27709, United States.

Bioorganic Chemistry
|May 25, 2021
PubMed

Keywords:
E/Z configurationFormulationMEK inhibitorSL 327Solubility

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