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Updated: Nov 4, 2025

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High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries
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Design concepts for DNA-encoded library synthesis
Bioorganic & Medicinal Chemistry
|May 25, 2021
Abstract:
An approach of building block (BB) inclusivity and atom efficient library schemes deliver the quality and diversity of DNA-encoded libraries best suited for small molecule drug discovery. In this Perspective, we offer key learnings in DEL design from a decade's worth of DEL-driven screening.

