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Related Experiment Video

Updated: Nov 4, 2025

Doppler Optical Coherence Tomography of Retinal Circulation
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Comparative analysis of 2 biometers using swept-source OCT technology.

Christophe Panthier1, Helene Rouger, Yoni Gozlan

  • 1From the Department of Ophthalmology, Rothschild Foundation, Paris, France.

Journal of Cataract and Refractive Surgery
|May 25, 2021
PubMed
Summary
This summary is machine-generated.

Two swept-source optical coherence tomography (SS-OCT) biometers showed high repeatability and agreement for cataract assessment. However, measurements like white-to-white distance were not interchangeable between devices.

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Area of Science:

  • Ophthalmology
  • Biometry
  • Optical Coherence Tomography

Background:

  • Accurate biometry is crucial for intraocular lens (IOL) calculations in cataract surgery.
  • Swept-source optical coherence tomography (SS-OCT) offers advanced biometry capabilities.
  • Comparing new biometry devices to established ones is essential for clinical adoption.

Purpose of the Study:

  • To evaluate the repeatability, agreement, and correlation between two SS-OCT biometers: IOLMaster 700 (biometer A) and ANTERION (biometer B).
  • To assess the interchangeability of key biometric parameters measured by both devices.

Main Methods:

  • Prospective comparative case series involving 63 patients (125 eyes) undergoing cataract assessment.
  • Measurements included axial length, keratometry, central corneal thickness, anterior chamber depth, lens thickness, and white-to-white (WTW) distance using both SS-OCT biometers.
  • Intraoperator repeatability, correlation, and agreement (Bland-Altman analysis) were calculated.

Main Results:

  • All intraoperator repeatability measurements were very high for both biometers.
  • High levels of correlation and agreement were found between biometer A and biometer B for most parameters.
  • Statistically significant differences were observed between the two biometers for all measurements (P < .05).

Conclusions:

  • The ANTERION (biometer B) demonstrated good repeatability and agreement compared to the IOLMaster 700 (biometer A).
  • However, not all measured parameters were interchangeable between the devices.
  • Particular discrepancies were noted in white-to-white distance and high keratometric values, impacting potential device interchangeability.