Analysis of chronic kidney disease among national hospitalization data with 14 million children

Xinmiao Shi1, Ying Shi2, Luxia Zhang3,4

  • 1Department of Pediatrics, Peking University First Hospital, Beijing, China.

BMC Nephrology
|May 26, 2021
PubMed

Insights

This study analyzed epidemiological data for pediatric chronic kidney disease (CKD) in China, finding secondary nephrosis and CAKUT as leading causes. These findings offer crucial insights for improving pediatric CKD diagnosis and treatment.

Area of Science:

  • Pediatric Nephrology
  • Epidemiology
  • Public Health

Background:

  • Chronic kidney disease (CKD) poses a significant health burden on pediatric populations globally.
  • Understanding the epidemiological landscape of pediatric CKD is essential for effective healthcare planning and intervention.

Purpose of the Study:

  • To determine basic epidemiological data on chronic kidney disease (CKD) among hospitalized pediatric patients in China.
  • To establish a foundation for policy development, registry implementation, and improved diagnosis and treatment strategies for pediatric CKD in China.

Main Methods:

  • Utilized data from the HQMS database, encompassing over 14 million pediatric inpatients from June 2013 to May 2017.
  • Employed International Classification of Diseases (ICD-10) codes to identify and extract records of pediatric inpatients diagnosed with CKD.

Main Results:

  • Identified 278,231 pediatric inpatients with CKD, representing 1.95% of the total pediatric inpatient population.
  • Revealed secondary nephrosis (37.95%) and congenital anomalies of the kidney and urinary tract (CAKUT) (24.61%) as the most common etiologies.
  • Noted IgA nephropathy as the predominant renal pathology, accounting for 51.17% of cases.

Conclusions:

  • This study provides a comprehensive descriptive analysis of hospitalized pediatric CKD patients in China.
  • The findings are vital for informing public health policies, guiding registry implementation, and enhancing the diagnosis, treatment, and prevention of pediatric CKD.
Abstract

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