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Analysis of Nephron Composition and Function in the Adult Zebrafish Kidney
Published on: August 9, 2014
Analysis of chronic kidney disease among national hospitalization data with 14 million children
Xinmiao Shi1, Ying Shi2, Luxia Zhang3,4
1Department of Pediatrics, Peking University First Hospital, Beijing, China.
Insights
This study analyzed epidemiological data for pediatric chronic kidney disease (CKD) in China, finding secondary nephrosis and CAKUT as leading causes. These findings offer crucial insights for improving pediatric CKD diagnosis and treatment.
Area of Science:
- Pediatric Nephrology
- Epidemiology
- Public Health
Background:
- Chronic kidney disease (CKD) poses a significant health burden on pediatric populations globally.
- Understanding the epidemiological landscape of pediatric CKD is essential for effective healthcare planning and intervention.
Purpose of the Study:
- To determine basic epidemiological data on chronic kidney disease (CKD) among hospitalized pediatric patients in China.
- To establish a foundation for policy development, registry implementation, and improved diagnosis and treatment strategies for pediatric CKD in China.
Main Methods:
- Utilized data from the HQMS database, encompassing over 14 million pediatric inpatients from June 2013 to May 2017.
- Employed International Classification of Diseases (ICD-10) codes to identify and extract records of pediatric inpatients diagnosed with CKD.
Main Results:
- Identified 278,231 pediatric inpatients with CKD, representing 1.95% of the total pediatric inpatient population.
- Revealed secondary nephrosis (37.95%) and congenital anomalies of the kidney and urinary tract (CAKUT) (24.61%) as the most common etiologies.
- Noted IgA nephropathy as the predominant renal pathology, accounting for 51.17% of cases.
Conclusions:
- This study provides a comprehensive descriptive analysis of hospitalized pediatric CKD patients in China.
- The findings are vital for informing public health policies, guiding registry implementation, and enhancing the diagnosis, treatment, and prevention of pediatric CKD.
Background:
The main purpose was to determine basic epidemiological data on CKD among hospitalized pediatric patients in China.
Methods:
Data from pediatric inpatients with CKD hospitalized from June 1, 2013 to May 31, 2017 were extracted from the electronic records of HQMS database, which includes over 14 million inpatients. Codes from the 10th revision of the International Classification of Diseases (ICD-10) were used to search the database.
Results:
A total of 524 primary diseases of CKD were included in this study. In all, there were 278 231 pediatric inpatients with CKD, which accounted for 1.95 % of the 14 250 594 pediatric inpatients registered in the HQMS database. The number of pediatric inpatients with CKD was 67 498 in 2013, 76 810 in 2014, 81 665 in 2015 and 82 649 in 2016, which accounted for 1.93 %, 1.93 %, 1.99 and 2.09 %, respectively, of the total population of pediatric inpatients. The etiology of CKD was secondary nephrosis in 37.95 % of cases, which ranked first and followed by CAKUT with a percentage of 24.61 %. Glomerular diseases and cystic kidney disease accounted for 21.18 and 5.07 %, respectively. Among all 278 231 patients, 6 581 (2.37 %) had a primary discharge diagnosis of CKD. The renal pathology findings of CKD showed that IgA accounted for 51.17 %.
Conclusions:
This study provides a descriptive analysis of the hospitalized population of pediatric CKD patients. Our study provides important, fundamental data for policy making and legislation, registry implementation and the diagnosis, treatment and prevention of CKD in China.
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