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Updated: Nov 4, 2025

Real-Time Cardiac Mapping with a Noninvasive Imageless Electrocardiographic Imaging System
Published on: April 11, 2025
Classification of COVID-19 electrocardiograms by using hexaxial feature mapping and deep learning
Mehmet Akif Ozdemir1,2, Gizem Dilara Ozdemir3,4, Onan Guren3
1Department of Biomedical Engineering, Faculty of Enigneering and Architecture, Izmir Katip Celebi University, 35620, Cigli, Izmir, Turkey. makif.ozdemir@ikcu.edu.tr.
This study introduces a novel deep learning method using Electrocardiogram (ECG) data for automated COVID-19 diagnosis. The approach achieves high accuracy, offering a potential new tool for early detection of the disease.
Area of Science:
- Cardiology
- Medical Imaging
- Artificial Intelligence
Background:
- Coronavirus disease 2019 (COVID-19) is a global pandemic requiring improved diagnostic methods.
- Current diagnostic techniques for COVID-19 have limitations, necessitating novel approaches.
- Early diagnosis of COVID-19 is critical for patient outcomes and disease management.
Purpose of the Study:
- To propose a novel deep learning framework for automated COVID-19 diagnosis using Electrocardiogram (ECG) data.
- To develop and validate a new hexaxial feature mapping technique for ECG representation.
- To assess the diagnostic performance of the proposed method in classifying COVID-19 cases.
Main Methods:
- A novel hexaxial feature mapping method was developed to convert 12-lead ECG data into 2D colorful images.
- Gray-Level Co-Occurrence Matrix (GLCM) was employed for feature extraction from ECG data.
- A new Convolutional Neural Network (CNN) architecture was designed and utilized for COVID-19 classification based on the generated ECG images.
Main Results:
- The proposed approach achieved 96.20% accuracy and 96.30% F1-Score in classifying COVID-19 versus normal ECG data.
- In a broader classification scenario, the method demonstrated 93.00% accuracy and 93.20% F1-Score for COVID-19 prediction.
- Experimental results confirmed the robustness and satisfactory performance of the deep learning model for COVID-19 detection.
Conclusions:
- Deep learning analysis of ECG data can effectively detect cardiovascular changes associated with COVID-19.
- ECG data holds potential as a non-invasive tool for the diagnosis of COVID-19.
- The developed framework can serve as a valuable decision-making support system for healthcare professionals in diagnosing COVID-19.
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