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Transdisciplinary Perspectives on Precision Medicine.

Hector F Myers1, Alecia M Fair2, Fernando Villalta3

  • 1Department of Medicine, Health & Society, Department of Psychology, and Department of African American & Diaspora Studies, Vanderbilt University, Nashville, Tennessee, USA.

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Summary
This summary is machine-generated.

Researchers with different backgrounds in social/behavioral science and human genomics perceive precision medicine and health disparities differently. Understanding these perceptions is key to improving transdisciplinary collaboration in genomics and health equity.

Keywords:
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Area of Science:

  • Genomics
  • Health Disparities Research
  • Precision Medicine

Background:

  • The Precision Medicine Health Disparities Collaborative aims to unite researchers from diverse backgrounds.
  • Understanding differing perceptions of precision medicine based on background is crucial for effective collaboration.

Purpose of the Study:

  • To investigate how educational background and current activities influence perceptions of precision medicine and health disparities.
  • To identify potential barriers and opportunities for transdisciplinary collaboration in this field.

Main Methods:

  • A cross-sectional survey was administered to Center members and others.
  • Data collected included educational background, current activities, and agreement with statements on genomics and health disparities.
  • Statistical analyses included Fisher's exact test and ordinal logistic regression.

Main Results:

  • Respondents with different educational backgrounds showed varying views on how lifestyle influences gene impact on disease risk (p=0.0009).
  • Current activities correlated with differing opinions on whether reducing healthcare access disparities improves precision medicine effectiveness (p=0.0008).
  • Concerns about genetic test usage due to racism and discrimination also varied by current activities (p=0.0011).

Conclusions:

  • Perceptions of precision medicine and health disparities differ significantly between individuals with social/behavioral science versus human genomics backgrounds.
  • These findings highlight the importance of addressing diverse perspectives to enhance transdisciplinary research and collaboration.
  • Identifying these differences can inform strategies to overcome barriers and foster greater equity in precision medicine.