CREATE: A New Data Resource to Support Cardiac Precision Health.

Area of Science:

• Health Informatics
• Cardiovascular Research
• Big Data Analytics

Background:

• Precision medicine and learning health systems necessitate comprehensive patient data.
• The CREATE database links four major data sources: Alberta Provincial Project for Outcome Assessment in Coronary Heart Disease (APPROACH), Sunrise Clinical Manager (SCM), Discharge Abstract Database (DAD), and National Ambulatory Care Reporting System (NACRS).

Purpose of the Study:

• To introduce a cardiovascular-specific database integrating diverse data sources.
• To enable big data analytics for advancing cardiac precision health initiatives.

Main Methods:

• Deterministic data linkage was employed to integrate SCM electronic medical record data with APPROACH clinical registry data.
• Further linkage to the Discharge Abstract Database (DAD) and National Ambulatory Care Reporting System (NACRS) incorporated inpatient and outpatient data.
• Linkage quality was validated against the Alberta Health Insurance Care Plan registry database.

Main Results:

• A high linkage success rate of 99.96% was achieved across the four databases.
• The CREATE database currently contains 30,984 patients and 35,753 catheterizations.
• The inpatient cohort represents 65.75% and the outpatient cohort 29.78% of the patient sample.

Conclusions:

• The CREATE database is established to support big data analytics in cardiac precision health.
• Management and secure housing within a high-performance computing environment are in place.