Related Experiment Video
Updated: Nov 4, 2025

06:45
Author Spotlight: Optimizing Hollow-Fiber Membranes for Continuous Liquid-Liquid Extraction of Medium-Chain Fatty Acids
Published on: August 9, 2024
1.5K
Volatile fatty acid platform - a cornerstone for the circular bioeconomy
F Velghe1, F De Wilde1, S Snellinx2
1OWS nv, Dok-Noord 5, 9000 Gent, Belgium.
FEMS Microbiology Letters
|May 26, 2021
Summary
Europe can transform urban biowaste into valuable volatile fatty acids (VFAs) for a circular economy. This biowaste valorization reduces landfilling and creates sustainable bio-based products.
Area of Science:
- Circular Economy
- Biotechnology
- Waste Management
Background:
- The EU generates over 100 million tonnes of urban biowaste annually, often under-utilized or landfilled.
- Current waste management practices in Europe miss significant opportunities for material and energy recovery from biowaste.
- A circular economy approach is essential for Europe to sustainably manage its biomass potential.
Purpose of the Study:
- To develop a volatile fatty acid platform (VFAP) for converting urban biowaste into valuable products.
- To explore the reprocessing of biowaste-derived volatile fatty acids (VFAs) into biopolymers, bioactive compounds, and chemical building blocks.
- To close material loops through effective biowaste valorization.
Main Methods:
- Investigated volatile fatty acid (VFA) production from various urban biowaste streams, including food waste, vegetable, garden, and fruit waste (VGF), and the organic fraction of municipal solid waste (OF-MSW).
- Employed a membrane filtration cascade (micro-, ultra-, nano-filtration, and reverse osmosis) for purifying and concentrating VFA effluent.
- Assessed socio-economic and legal aspects of the VFAP technology.
Main Results:
- Achieved average VFA yields of 627 g COD/kg OM (food waste), 448 g COD/kg OM (VGF), and 384 g COD/kg OM (OF-MSW).
- Concentrations of VFAs in the effluent ranged from 12-48 g/L (food waste), 6-40 g/L (VGF), and 13-26 g/L (OF-MSW).
- The membrane filtration cascade proved effective for VFA purification, creating a suitable carbon source for fermentation.
Conclusions:
- The VFAP technology offers a viable solution for treating urban biowaste and recovering valuable VFAs.
- Purified VFAs can serve as a sustainable feedstock for producing biopolymers, bioactive compounds, and chemical building blocks.
- The VFAP is expected to play a significant role in future organic waste treatment and bio-based production strategies, aligning with societal and market demands.
Related Concept Videos
Overview of Fatty Acid Metabolism
32.8K
Lipids also are sources of energy that power cellular processes. Like carbohydrates, lipids are composed of carbon, hydrogen, and oxygen, but these atoms are arranged differently. Most lipids are nonpolar and hydrophobic. Major types include fats and oils, waxes, phospholipids, and steroids.
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
Fatty acids are catabolized in a process called beta-oxidation, which takes place in the matrix of the mitochondria and converts their fatty acid chains into two-carbon units of acetyl groups. The acetyl...
32.8K
Lipid Catabolism
420
Triglycerides serve as crucial long-term energy storage molecules in microorganisms, providing a dense source of metabolic energy. Their breakdown is mediated by lipases, which hydrolyze triglycerides into glycerol and free fatty acids. Each of these components follows distinct metabolic pathways, ultimately contributing to ATP synthesis and cellular energy homeostasis.Glycerol MetabolismGlycerol, released from triglyceride hydrolysis, is phosphorylated by glycerol kinase to form...
420
Biosynthesis of Lipids
236
Microbial membranes exhibit remarkable diversity in lipid composition, reflecting evolutionary adaptations to various environmental conditions. The three domains of life—Bacteria, Archaea, and Eukarya—synthesize membrane lipids through distinct biosynthetic pathways, leading to fundamental structural differences that impact membrane stability, function, and adaptability.Fatty Acid-Based Lipids in Bacteria and EukaryaBacteria and eukaryotes share a common fatty acid biosynthesis...
236
Lipids as Anchors
6.5K
In the plasma membrane, the lipids forming the bilayer can also act as an anchor to tether proteins to the membrane. The three main types of lipid anchors found in eukaryotes are – prenyl groups, fatty acyl groups, and glycosylphosphatidylinositol or GPI groups. Prenyl and fatty acyl groups act as anchors on the cytosolic surface of the membrane, whereas GPI anchors proteins on the extracellular side.
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
The carboxy-terminal of most of the prenylated proteins, such as Ras proteins, contains...
6.5K
Fates of Pyruvate
9.6K
Pyruvate is the end product of glycolysis, where glucose is oxidized to pyruvate, simultaneously reducing NAD+ to NADH. Two molecules of ATP are also produced by substrate-level phosphorylation.
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
In aerobic organisms, pyruvate is metabolized via the citric acid cycle to produce reduced coenzymes NADH and FADH2. These coenzymes are then oxidized in the electron transport chain to produce ATP and, in the process, regenerate the NAD+ and FAD. As seen in some cell types and organisms, fermentation...
9.6K
Microbial Fermentation
745
Fermentation is a crucial anaerobic metabolic process that enables microbes to derive energy from sugar without relying on oxygen or an electron transport chain. This process is fundamental to various biological and industrial applications and is classified based on the metabolic products generated.Role of Pyruvate in FermentationPyruvate and its derivatives serve as key electron acceptors in fermentative pathways. The oxidation of NADH to regenerate NAD+ is essential for the continuation of...
745

