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Non-scarring patchy alopecia: What else, apart from alopecia areata?
Luigi Pisano1, Michela Di Pietro, Raffaella Santi2
1Dermatology Unit, Department of Health Sciences, University of Florence, Florence, Italy.
Journal of Cutaneous Pathology
|May 26, 2021
Summary
A woman with lymphoma experienced alopecia areata-like hair loss and enlarged lymph nodes. Treatment led to complete hair regrowth and lymphoma remission, indicating a link between the conditions.
Area of Science:
- Oncology
- Dermatology
- Hematology
Background:
- The case involves a 67-year-old woman with a history of stable IgM monoclonal gammopathy of undetermined significance.
- She presented with a 3-month history of patchy alopecia areata (AA)-like hair loss and painful enlarged lymph nodes.
Observation:
- Scalp biopsy revealed B-cell lymphoid infiltrates, suggesting marginal zone B-cell lymphoma (MZL).
- Staging confirmed nodal MZL with secondary cutaneous involvement.
Findings:
- Immunochemotherapy for the diagnosed lymphoma resulted in complete remission of the alopecia.
- Hair regrowth occurred without evidence of scarring.
Implications:
- This case highlights a potential association between marginal zone B-cell lymphoma and secondary alopecia areata.
- Successful lymphoma treatment can lead to resolution of associated dermatological symptoms.
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