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A simple and feasible atom-precise biotinylated Cu(i) complex for tumor-targeted chemodynamic therapy
Bi Luo1, Liguang Chen, Zhaoguo Hong
1State Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences, Guangxi Normal University, Guilin 541004, P. R. China. huangfp2010@163.com liangzhang319@163.com.
Chemical Communications (Cambridge, England)
|May 26, 2021
Abstract:
A simple and feasible atom-precise biotinylated Cu(i) complex, which can catalyze H2O2 overexpressed commonly in the tumor microenvironment to produce ˙OH through a Fenton-like reaction, was prepared and employed as an effective agent for tumor-targeted chemodynamic therapy.
