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Myocardiotoxicity of 5 fluorouracil
B Coronel1, O Madonna, A Mercatello
1Département de Néphrologie, Hôpital Edouard Herriot, Lyon, France.
Intensive Care Medicine
|January 1, 1988
Abstract:
We report a case of specific myocardiotoxicity due to 5 F.U. not previously described in man. A 41-year-old man was admitted to the ICU for heart and renal failure, appearing 24 h after 5 days treatment with 5 F.U. and cis-platinum. Dopamine was necessary to maintain blood pressure. Two-D echocardiography and a right heart catheterisation confirmed the alteration of myocardial contractility. After 2 weeks a complete cardiac recovery occurred.