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Updated: Nov 4, 2025

Mass Isolation and In Vitro Cultivation of Intramolluscan Stages of the Human Blood Fluke Schistosoma Mansoni
Published on: January 14, 2018
Cerebral mansoni schistosomiasis: a systematic review of 33 cases published from 1989 to 2019
Igor Silvestre Bruscky1, Dayanne Mota Veloso Bruscky2, Fabio Lopes de Melo3
1University of Pernambuco, 310 Arnobio Marques Street, Santo Amaro, Recife, Pernambuco, Brazil 50100-130.
Background:
We investigated the epidemiology, clinical presentation and outcomes of individuals affected by cerebral schistosomiasis.
Methods:
This systematic review was planned in accordance with current guidelines for performing comprehensive systematic reviews and meta-analysis, including the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline.
Results:
Most of patients presented with seizures (48.5%), which is a non-specific symptom despite its high prevalence. There was no specific clinical manifestation that could help the diagnosis, which was made in 69.7% by histopathological analysis of brain tissue.
Conclusions:
Seizures are a non-specific symptom to diagnose patients with cerebral schistosomiasis and accurate clinical indicators need to be derived through further studies.

