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Updated: Nov 4, 2025

Therapy Interventions for Upper Limb Amputees Undergoing Selective Nerve Transfers
Published on: October 29, 2021
Current concepts in diagnosis and management of common upper limb nerve injuries in children
Nunzio Catena1, Giovanni Luigi Di Gennaro2, Andrea Jester3
1Hand Surgery and Microsurgery Unit - Pediatric Orthopedic and Traumatology Unit - Azienda Ospedaliera SS Antonio e Biagio e Cesare Arrigo, Alessandria, Italy.
Insights
Diagnosing closed peripheral nerve injuries (PNI) in children can be challenging. This article offers guidance on managing pediatric upper limb PNI, distinguishing it from adult treatment.
Area of Science:
- Pediatric Orthopedics
- Neurology
- Traumatology
Background:
- Peripheral nerve injuries (PNI) are common in children, often associated with fractures and soft tissue damage.
- Diagnosing closed PNI in pediatric patients can be difficult due to challenges in clinical assessment, compounded by pain and anxiety.
- While most pediatric PNIs are neuroapraxias with spontaneous recovery, uncertainties exist regarding optimal management for closed injuries.
Purpose of the Study:
- To analyze key aspects of closed peripheral nerve injuries in the upper limb in children.
- To provide recommendations for the timely and accurate management of pediatric upper limb PNI.
- To identify differences in PNI treatment approaches between pediatric and adult populations.
Main Methods:
- Review and analysis of current literature on pediatric upper limb peripheral nerve injuries.
- Evaluation of diagnostic challenges and clinical assessment techniques in children.
- Comparison of management strategies, including electrophysiological testing and surgical intervention timing, for pediatric versus adult PNI.
Main Results:
- Delayed diagnosis of closed PNI in children is a significant concern due to assessment limitations.
- Specific criteria for electrophysiological examination and observation periods for spontaneous recovery in pediatric PNI require further clarification.
- Treatment decisions for pediatric PNI, particularly regarding surgical intervention, may differ from adult protocols.
Conclusions:
- Standardized guidelines are needed for the diagnosis and management of closed peripheral nerve injuries in the pediatric upper limb.
- Further research should focus on optimizing electrodiagnostic strategies and determining appropriate surgical thresholds in children.
- Tailoring PNI treatment to the unique physiological and developmental characteristics of pediatric patients is crucial for optimal outcomes.
Abstract:
Peripheral nerve injuries (PNI) of the upper limb are a common event in the paediatric population, following both fractures and soft tissues injuries. Open injuries should in theory be easier to identify and the repair of injured structures performed as soon as possible in order to obtain a satisfying outcome. Conversely, due to the reduced compliance of younger children during clinical assessment, the diagnosis of a closed nerve injury may sometimes be delayed. As the compliance of patients is influenced by pain, anxiety and stress, the execution of the clinical manoeuvres intended to identify a loss of motor function or sensibility, can be impaired. Although the majority of PNI are neuroapraxias resulting in spontaneous recovery, there are open questions regarding certain aspects of closed PNI, e.g. when to ask for electrophysiological exams, when and how long to wait for a spontaneous recovery and when a surgical approach becomes mandatory. The aim of the article is therefore to analyse the main aspects of the different closed PNI of the upper limb in order to provide recommendations for timely and correct management, and to determine differences in the PNI treatment between children and adults.
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