Related Experiment Video
Updated: Nov 4, 2025

09:41
A Simple Critical-sized Femoral Defect Model in Mice
Published on: March 15, 2015
15.4K
Functional limitations caused by simple bone cysts.
Amy Behman1,2,3, Brian Feldman3,4, Andrea Doria3,5
1Division of Orthopaedic Surgery, Department of Surgery, University of Toronto, Toronto, Canada.
Journal of Children'S Orthopaedics
|May 27, 2021
Summary
Simple bone cysts (SBCs) in children do not significantly impact physical function but can influence their thoughts on physical activity. This suggests a need for outcome tools that assess both function and illness perception.
Area of Science:
- Pediatric Orthopedics
- Rehabilitation Medicine
- Child Psychology
Background:
- Benign bone lesions, such as simple bone cysts (SBCs), are common in children.
- The functional impact of SBCs on children's daily lives is not well understood.
- Existing research often overlooks the psychological and perceptual effects of these conditions.
Purpose of the Study:
- To comprehensively assess the functional disability associated with simple bone cysts (SBCs) in children.
- To integrate qualitative and quantitative data for a nuanced understanding of SBC impact.
- To explore how SBCs affect children's participation in activities and their perceptions of health.
Main Methods:
- Convergent parallel mixed methods design combining quantitative and qualitative data.
- Quantitative analysis: 130 children with SBC assessed using the Activities Scale for Kids (ASK) for physical function.
- Qualitative analysis: Interviews with 10 children and parents regarding activity participation and environmental interactions.
Main Results:
- Quantitative findings: 35% of children achieved maximum scores on the ASK, indicating high physical function.
- Perception of illness: 65% of children reported no medical needs, viewing SBCs as non-chronic.
- Qualitative findings: Most children reported minimal impact on activity participation but noted increased caution during play, affecting perceived effort rather than actual participation.
Conclusions:
- SBC diagnosis does not significantly impair physical function but alters children's mindset towards physical activity.
- Potential ceiling effects in current physical function assessment tools may mask subtle impacts.
- Future outcome measures should incorporate illness perceptions alongside physical function for a holistic assessment of SBCs.
Related Concept Videos
Bone Disorders
4.6K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
4.6K
The Functions of the Skeletal System
5.2K
The most apparent functions of the skeletal system are support, protection, and movement. However, bone tissue also performs several other critical metabolic functions. For one, the bone matrix acts as a reservoir for a number of minerals important to the functioning of the body, especially calcium and phosphorus. These minerals, present in the bone tissue, can be released back into the bloodstream when required. Calcium ions, for example, are essential for muscle contractions and controlling...
5.2K
Compact Bone
14.7K
Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...
14.7K
Classification of Bones
8.6K
The bones of the human skeletal system are of varied shapes, sizes, and functions. They can be classified based on their shape and function into four major classes: long bones, short bones, flat bones, and irregular bones. Some classifications include a fifth type, the sesamoid bones, as a separate class, whereas others categorize them under short bones.
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
Long and Short Bones
The appendicular skeleton, particularly the upper and lower limbs, is primarily made of long and short bones. The...
8.6K
Sutures of the Skull
8.9K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
8.9K
Spongy Bone
6.6K
All bones comprise an outer layer of compact bone, and an interior made up of spongy bone tissue, also called cancellous or trabecular bone. In long bones, spongy bone tissue is mainly found in the interior of the epiphyses (broad ends of the bone).
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
Spongy bone is more porous, and less dense compared to compact bone. It is composed of concentric lamellae that are arranged irregularly to form the trabecular network. In some bones, the spaces between trabeculae contain red marrow, where...
6.6K

