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COVID-19 in Children: A Narrative Review

Jennifer F Ha1

  • 1Department of Paediatrics Otolaryngology-Head & Neck Surgery, Perth Children's Hospital, 15 Hospital Avenue, Nedlands 6009, Western Australia, Australia.

Current Pediatric Reviews
|May 27, 2021
PubMed

Insights

Children infected with coronavirus disease 2019 (COVID-19) generally experience milder symptoms and have limited virus growth. Continued research is vital for managing this vulnerable population effectively.

Area of Science:

  • Virology
  • Pediatrics
  • Epidemiology

Background:

  • The COVID-19 pandemic, caused by a novel zoonotic coronavirus, affects all age groups.
  • This review focuses on pertinent information regarding COVID-19 in pediatric populations.
  • The scientific community has rapidly generated extensive data since the pandemic's onset.

Purpose of the Study:

  • To summarize key information concerning COVID-19 in children.
  • To provide an overview of the disease's impact on pediatric patients.

Main Methods:

  • A comprehensive literature search was performed using PubMed, MEDLINE, and Embase databases.
  • Keywords included "COVID 19" and "children", with searches updated in April 2020.
  • Bibliographic searches and abstract screening were conducted for narrative review inclusion.

Main Results:

  • The review discusses the etiology, transmission, incubation period, and pathophysiology of COVID-19.
  • Clinical features, complications, and management strategies for COVID-19 in children are detailed.
  • Information on SARS-CoV-2 aetiology, transmission, and clinical presentation in pediatric cases is synthesized.

Conclusions:

  • COVID-19 in children typically presents with milder disease courses and limited viral replication.
  • Many pediatric cases are asymptomatic, highlighting a different disease dynamic compared to adults.
  • Further research is crucial for optimizing the timely management of COVID-19 in children.
Abstract

Keywords:
COVID-19SARS-CoV-2.asymptomaticchildreninfantsneonatespediatricreview

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