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Related Concept Videos

Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications01:25

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Peritoneal dialysis (PD) is a medical process that removes waste products and excess fluid from the body using the peritoneal membrane as a natural filter.Peritoneal Dialysis MethodsSeveral methods can be used for peritoneal dialysis, including Acute Intermittent Peritoneal Dialysis, Continuous Ambulatory Peritoneal Dialysis, and Automated Peritoneal Dialysis, also known as Continuous Cyclic Peritoneal Dialysis.Acute Intermittent Peritoneal Dialysis (AIPD) is used for patients with uremic...
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Esophageal perforations manifest in various clinical forms, influenced by factors such as the perforation's cause and location (cervical, intrathoracic, or intra-abdominal), the extent of contamination, and potential injury to adjacent mediastinal structures. The timing between the perforation occurrence and treatment initiation also affects the clinical presentation.
Clinical Manifestations:
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In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
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Esophageal perforation is a severe medical condition characterized by a breach in the integrity of the esophageal wall. This breach can occur due to various factors such as trauma, medical procedures, or underlying diseases. When the esophageal wall is compromised, it allows food, fluids, and digestive juices into the chest cavity or adjacent structures, leading to potential complications and health risks.
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Related Experiment Video

Updated: Nov 4, 2025

Colon Ascendens Stent Peritonitis CASP - a Standardized Model for Polymicrobial Abdominal Sepsis
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Severe eosinophilic peritonitis caused by intraperitoneal vancomycin administration.

Chih-Yao Hsu, Ding-Jie Lee, Shih-Hua Lin

    Clinical Nephrology
    |May 27, 2021
    PubMed
    Summary

    Non-infectious eosinophilic peritonitis (EP) can occur in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). Vancomycin-induced EP presents with negative cultures and resolves with steroid therapy.

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    Area of Science:

    • Nephrology
    • Internal Medicine
    • Pathology

    Background:

    • Non-infectious eosinophilic peritonitis (EP) is often unrecognized in uremic patients on continuous ambulatory peritoneal dialysis (CAPD).
    • This can lead to inappropriate management and prolonged patient suffering.

    Observation:

    • A 56-year-old male on CAPD presented with peritonitis symptoms and Enterococcus faecalis infection.
    • Initial treatment with intraperitoneal vancomycin improved symptoms, but recurrent turbid dialysate with high eosinophil counts and negative cultures emerged.
    • Peripheral eosinophilia was also noted.

    Findings:

    • The patient's eosinophilic peritonitis and peripheral eosinophilia resolved completely after discontinuing vancomycin and initiating oral steroid therapy.
    • This suggests vancomycin as the causative agent for drug-induced eosinophilic peritonitis.

    Implications:

    • Vancomycin-induced eosinophilic peritonitis should be considered in CAPD patients with recurrent turbid dialysate, high eosinophils, and negative cultures.
    • Prompt recognition and cessation of the offending antibiotic, along with steroid treatment, can prevent unnecessary investigations and complications.