Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Culture01:17

Stem Cell Culture

5.7K
Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
5.7K
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

4.3K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.3K
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

5.5K
Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...
5.5K
Adult Stem Cells01:33

Adult Stem Cells

31.0K
Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously...
31.0K
Stem Cell Niche01:26

Stem Cell Niche

5.6K
The stem cell niche is the dynamic microenvironment where stem cells reside. Inside these niches, the cells may remain undifferentiated, undergo high self-renewal, or become lineage-specific progenitors. Stem cells coexist with other niche cells, such as stromal cells. They also interact closely with the ECM. Cell-cell and cell-matrix communication occur via adhesion molecules or soluble factors that signal the stem cells and determine their fate. Stromal cells also provide survival signals to...
5.6K
Embryonic Stem Cells00:58

Embryonic Stem Cells

29.5K
Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
29.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Multi-Modular Human-AI Workflow for LLM-Assisted Thematic Analysis: Application to COPD Telerehabilitation Interviews.

Studies in health technology and informatics·2026
Same author

Association of Remote Patient Monitoring with Care Utilization in Patients with Chronic Cardiopulmonary Conditions.

Studies in health technology and informatics·2026
Same author

Machine Learning Approaches for Mortality Prediction in ARDS.

Studies in health technology and informatics·2026
Same author

Estimating Mosaic Loss of the Y Chromosome in Male Bladder Cancer Participants Using "All of Us" Data.

Studies in health technology and informatics·2026
Same author

Early Prediction of Delirium in ICU Patients Using Machine Learning Analysis of Admission Data.

Studies in health technology and informatics·2026
Same author

Multimodule Human-Artificial Intelligence Collaboration Pipeline for Large Language Model-Assisted Thematic Analysis Across Digital Health Interview Studies: Comparative Evaluation Study.

JMIR medical informatics·2026

Related Experiment Video

Updated: Nov 4, 2025

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
09:08

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer

Published on: January 12, 2020

6.9K

Introducing a Platform for Integrating and Sharing Stem Cell Research Data.

Kirill Borziak1, Irena Parvanova1, Joseph Finkelstein1

  • 1Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Studies in Health Technology and Informatics
|May 27, 2021
PubMed
Summary
This summary is machine-generated.

A new platform, ReMeDy, harmonizes diverse stem cell data for regenerative medicine research. This informatics solution integrates product, subject, and omics information, enhancing collaboration and knowledge generation from shared stem cell data.

Keywords:
Induced pluripotent stem cellcommon data elementsdatabaseharmonization

More Related Videos

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
10:12

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

18.8K
Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform
11:08

Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform

Published on: January 13, 2019

12.6K

Related Experiment Videos

Last Updated: Nov 4, 2025

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
09:08

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer

Published on: January 12, 2020

6.9K
Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues
10:12

Droplet Barcoding-Based Single Cell Transcriptomics of Adult Mammalian Tissues

Published on: January 10, 2019

18.8K
Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform
11:08

Exploring the Effects of Spaceflight on Mouse Physiology using the Open Access NASA GeneLab Platform

Published on: January 13, 2019

12.6K

Area of Science:

  • Regenerative Medicine
  • Bioinformatics
  • Stem Cell Biology

Background:

  • Advancements in regenerative medicine necessitate better standardization and sharing of stem cell products.
  • Existing databases lack a unified platform for heterogeneous stem cell data within a project-based framework.

Purpose of the Study:

  • To introduce ReMeDy, an intelligent informatics platform designed to integrate diverse stem cell product characteristics with study subject and omics data.
  • To provide a harmonized, project-based framework for stem cell information management.

Main Methods:

  • Developed ReMeDy, a platform utilizing predefined ontologies for data validation.
  • Stored harmonized heterogeneous data in a relational database.
  • Tested ReMeDy functionality using publicly available induced pluripotent stem cell (iPSC) projects across various evaluation stages (in vitro, preclinical, intervention).

Main Results:

  • Demonstrated ReMeDy's robustness in storing diverse iPSC data.
  • Showcased seamless harmonization of heterogeneous common data elements.
  • Highlighted the platform's potential for knowledge generation through aggregated, shared data.

Conclusions:

  • ReMeDy offers a robust solution for managing and integrating diverse stem cell data.
  • The platform facilitates scientific collaboration and accelerates regenerative medicine advancements.
  • Future development includes crowdsourcing and automated metadata abstraction to expand curated projects.