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Double Direct Injection of Blood into the Cisterna Magna as a Model of Subarachnoid Hemorrhage
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Published on: August 30, 2020

Hypertensive Intracerebral Hemorrhage in Young Patients From a Tertiary Care Center in Saudi Arabia: An Observational

Aishah Albakr1, Abdullah AlFajri1, Ahmad Almatar1

  • 1Department of Neurology, College of Medicine, Imam Abdulrahman Bin Faisal University, Dammam, Eastern Province, Saudi Arabia.

The Primary Care Companion for CNS Disorders
|May 27, 2021
PubMed

Insights

Younger patients with hypertensive intracerebral hemorrhage (ICH) present with more severe symptoms and worse outcomes. Aggressive monitoring and treatment are crucial for this demographic.

Area of Science:

  • Neurology
  • Cardiovascular Medicine
  • Public Health

Background:

  • Intracerebral hemorrhage (ICH) in young adults is uncommon but significant.
  • Hypertensive ICH is a major cause of stroke, particularly in younger populations.
  • Understanding age-related differences in hypertensive ICH is vital for targeted interventions.

Purpose of the Study:

  • To investigate the clinical characteristics and outcomes of hypertensive ICH in very young (18-45 years) and young (46-55 years) adult patients.
  • To compare clinical and radiologic features between these two age groups.
  • To identify factors influencing clinical outcomes in younger hypertensive ICH patients.

Main Methods:

  • Retrospective study of 63 patients aged 18-55 with hypertensive ICH (April 2014 - April 2019).
  • Patients were divided into two groups: 18-45 years (Group 1) and 46-55 years (Group 2).
  • Comparison of clinical/radiologic features, risk factors, and long-term outcomes; analysis of factors affecting outcomes.

Main Results:

  • Group 1 (18-45 years) had a higher prevalence of diabetes (OR=4.65) and worse outcomes (OR=5.14).
  • Patients in Group 1 presented with higher NIH Stroke Scale scores (15.7±4.6), lower Glasgow Coma Scale (GCS) scores (OR=3.33), and increased risk of intubation (OR=2.79).
  • Higher ICH volume (21±18) was observed in Group 1; low GCS, hematoma volume, and intraventricular extension independently predicted worse outcomes.

Conclusions:

  • Relatively young patients with hypertensive ICH exhibit a higher prevalence of diabetes and poorer clinical outcomes compared to older patients.
  • These younger patients often present with more severe neurological deficits and larger hematomas.
  • More aggressive monitoring and treatment strategies are recommended for younger individuals diagnosed with hypertensive ICH.

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