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Related Concept Videos

Skin Diseases and Disorders01:23

Skin Diseases and Disorders

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Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
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Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
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Dermis
The dermis might be considered the "core" of the integumentary system, as distinct from the epidermis and hypodermis. It contains blood and lymph vessels, nerves, and other structures, such as hair follicles and sweat glands. The dermis is made of two layers of connective tissue that comprise an interconnected mesh of elastin and collagenous fibers, produced by fibroblasts.
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Hypersensitivity, also known as a hypersensitivity reaction or allergic reaction, is a condition where the body's immune system reacts abnormally to a foreign substance. Such substances, that cause hypersensitivity are referred to as an allergen, could be something typically harmless to most people, like pollen or certain foods.
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Pediatric patient dosages diverge from adults due to disparities in body surface area, total body water, and extracellular fluid per kilogram of body weight. The dosing regimen considers the variations in pharmacokinetics and pharmacology across distinct age groups, encompassing preterm newborns, infants, young children, older children, and adolescents. Calculation of pediatric patient doses is predicated on determining body surface area, which exhibits a superior correlation with the child's...
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Resolving Water, Proteins, and Lipids from In Vivo Confocal Raman Spectra of Stratum Corneum through a Chemometric Approach
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Contact Dermatitis in Children.

Divya Seth, Pavadee Poowuttikul, Deepak Kamat

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    |May 28, 2021
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    Summary
    This summary is machine-generated.

    Contact dermatitis (CD) is a common pediatric skin condition often underrecognized in children. Early diagnosis and management are crucial for addressing allergic and irritant forms, which present with varied skin lesions.

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    Area of Science:

    • Pediatric Dermatology
    • Allergen Exposure
    • Skin Health

    Background:

    • Contact dermatitis (CD) is prevalent in children, presenting diagnostic challenges due to polymorphic skin lesions.
    • Both allergic and irritant CD forms cause significant issues but are frequently underdiagnosed in pediatric patients.

    Purpose of the Study:

    • To review the pathophysiology, diagnosis, and management of contact dermatitis in the pediatric population.
    • To highlight common causative agents and diagnostic methods for pediatric CD.

    Main Methods:

    • Literature review focusing on pediatric contact dermatitis.
    • Discussion of diagnostic approaches including patch testing.
    • Analysis of common allergens like metals, fragrances, and preservatives.

    Main Results:

    • Contact dermatitis in children often mimics other pediatric skin conditions.
    • Patch testing, detailed history, and physical examination are key diagnostic tools.
    • Metals, fragrances, and preservatives are identified as frequent triggers in pediatric CD.

    Conclusions:

    • Contact dermatitis is an underrecognized yet significant condition in pediatric dermatology.
    • Accurate diagnosis and appropriate management are essential for improving outcomes in children with CD.
    • Awareness of common pediatric CD triggers aids in prevention and treatment.