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First case report of acute cholangitis secondary to Cronobacter sakazakii

Syeda Sahra1, Abdullah Jahangir2, Neville Mobarakai2

  • 1Staten Island University Hospital, 475-Seaview Avenue, Staten Island, NY, 10305, USA. ssahra@northwell.edu.

BMC Infectious Diseases
|May 28, 2021
PubMed
Abstract

Insights

This case study reports the first instance of Cronobacter sakazakii (C. sakazakii) causing acute cholangitis in an 81-year-old male. The patient recovered after treatment with carbapenem for C. sakazakii bacteremia and cholangitis.

Area of Science:

  • Infectious Diseases
  • Microbiology
  • Gastroenterology

Background:

  • Cronobacter sakazakii (C. sakazakii) is an opportunistic pathogen linked to meningitis, enterocolitis, and bacteremia.
  • Historically, C. sakazakii infections have not been associated with acute cholangitis in humans.

Observation:

  • An 81-year-old male with significant comorbidities presented with severe abdominal pain.
  • The patient underwent percutaneous cholecystostomy tube placement due to concerns for pancreatitis, cholangitis, and cholecystitis.

Findings:

  • Blood and biliary fluid cultures confirmed C. sakazakii bacteremia and cholangitis.
  • The patient showed clinical improvement following carbapenem treatment.

Implications:

  • This case represents the first documented instance of C. sakazakii causing acute cholangitis.
  • Highlights the potential for C. sakazakii to cause diverse infections, even in immunocompromised adults.
Keywords:
CholangitisCholecystitisCronobacter sakazakiiGallbladder infection

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