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Biventricular conversion after Fontan completion: A preliminary experience.

Ilias P Doulamis1, Supreet P Marathe1, Breanna Piekarski1

  • 1Department of Cardiac Surgery, Boston Children's Hospital, Harvard Medical School, Boston, Mass.

The Journal of Thoracic and Cardiovascular Surgery
|May 28, 2021
PubMed
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Biventricular conversion after Fontan circulation is feasible, improving ventricular function. However, outcomes are poorer for patients with failing Fontan physiology compared to elective cases.

Area of Science:

  • Cardiovascular Surgery
  • Pediatric Cardiology
  • Congenital Heart Disease

Background:

  • The Fontan circulation is a palliative procedure for single-ventricle physiology.
  • Takedown of Fontan circulation and conversion to biventricular physiology is a complex procedure.
  • Failing Fontan physiology necessitates alternative treatment strategies.

Purpose of the Study:

  • To evaluate the feasibility and outcomes of biventricular conversion after Fontan circulation.
  • To assess the impact of biventricular conversion on ventricular function.
  • To compare outcomes between failing Fontan physiology and elective takedown.

Main Methods:

  • Retrospective analysis of 23 patients undergoing Fontan takedown and biventricular conversion (2007-2020).
Keywords:
Fontanbiventricular conversioncongenital heart defectfailing Fontanventricular recruitment

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  • Definition of failing Fontan physiology: pressure >15 mm Hg and/or complications.
  • Inclusion of staged ventricular recruitment in a subset of patients.
  • Main Results:

    • Biventricular conversion significantly increased indexed end-diastolic volume, end-systolic volume, and ventricular mass of the nondominant ventricle.
    • Overall mortality was 22%, with 4% early death.
    • Two-year survival for failing Fontan was 72.7%, versus 100% for elective takedown. Predictors of mortality included left dominant atrioventricular canal defect and early era of surgery.

    Conclusions:

    • Biventricular conversion, primary or staged, is feasible for patients with prior Fontan procedures.
    • It offers an alternative to transplantation for failing Fontan physiology.
    • Outcomes are less favorable in failing Fontan cases compared to elective takedowns; optimal timing requires further study.