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Seronegative Arthritis as a Complication of Whipple's Disease
Rebecca DeBoer1, Sahani Jayatilaka1, Anthony Donato1
1Department of Medicine, Reading Hospital, Reading, PA, USA.
Abstract:
Whipple's disease (WD) is an uncommon cause of seronegative arthritis. WD is known for its gastrointestinal symptoms of diarrhea, weight loss, and abdominal pain. However, arthritis may precede gastrointestinal symptoms by 6 to 7 years. We describe a case of an 85-year-old Caucasian male with multiple joint complaints, not responsive to traditional treatments for conditions such as rheumatoid arthritis and osteoarthritis. We suggest that WD be considered for seronegative arthritis especially affecting large joints.
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