Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Fatal food-induced anaphylaxis.

J W Yunginger1, K G Sweeney, W Q Sturner

  • 1Department of Pediatrics, Mayo Medical School, Mayo Clinic and Foundation, Rochester, Minn 55905.

JAMA
|September 9, 1988
PubMed
Summary

Fatal food-induced anaphylaxis is rare but serious. Prompt epinephrine administration is crucial for atopic individuals experiencing severe allergic reactions to food, especially when away from home.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Response to correspondence from McCarthy et al. regarding maternal sepsis screening and the role of the neutrophil-to-lymphocyte ratio.

International journal of obstetric anesthesia·2025
Same author

Early viscoelastometric guided fibrinogen replacement combined with escalation of clinical care reduces progression in postpartum haemorrhage: a comparison of outcomes from two prospective observational studies.

International journal of obstetric anesthesia·2024
Same author

Evaluation of peer-mediated systems navigation for ageing families of individuals with developmental disabilities.

Journal of intellectual disability research : JIDR·2023
Same author

GSK2245035, a TLR7 agonist, Does Not Increase Pregnancy Loss in Cynomolgus Monkeys.

Journal of reproductive immunology·2020
Same author

Oxidative stress serves as a key checkpoint for IL-33 release by airway epithelium.

Allergy·2017
Same author

Planning for Uncertainty and Fallbacks Can Increase the Number of Transplants in a Kidney-Paired Donation Program.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015

Area of Science:

  • Allergy and Immunology
  • Clinical Medicine
  • Toxicology

Background:

  • Fatal food-induced anaphylaxis is a rarely documented clinical event.
  • Anaphylaxis represents a severe, life-threatening allergic reaction.
  • Understanding risk factors is critical for prevention and management.

Observation:

  • Seven cases of fatal food-induced anaphylaxis were identified over 16 months.
  • Victims were atopic, with prior anaphylactic episodes to specific foods (peanut, pecan, crab, fish).
  • Reactions often occurred after food ingestion away from home.

Findings:

  • Contributing factors to fatal outcomes included symptom denial, alcohol consumption, inadequate treatment with oral antihistamines, and glucocorticoid use.
  • Epinephrine was not administered promptly in any of the fatal cases.

Related Experiment Videos

  • Elevated IgE antibodies to the causative food were confirmed in postmortem samples.

    • Implications:

    • Food-allergic individuals must carry and self-administer epinephrine immediately upon symptom onset.
    • Healthcare providers should educate patients on prompt epinephrine use and recognize anaphylaxis severity factors.
    • Emergency medical services should consider cricothyrotomy for airway management in severe anaphylaxis.